Primary Site >> Colorectal Cancer

Gene >> ANGPT2

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Ref: Hepatic expression of ANG2 RNA in metastatic colorectal cancer.
PMID: 14768007
Ref: Inhibition of in vivo tumor angiogenesis and growth via systemic delivery of an angiopoietin 2-specific RNA aptamer.
PMID: 17950331
Ref: Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer.
PMID: 19826039
Ref: Complementary actions of inhibitors of angiopoietin-2 and VEGF on tumor angiogenesis and growth.
PMID: 20197469
Ref: [Identification of protein markers for serum diagnosis of cancer based on microRNA expression profiling].
PMID: 21634125
Ref: A human neutralizing antibody specific to Ang-2 inhibits ocular angiogenesis.
PMID: 21851472
Ref: Higher metastatic efficiency of KRas G12V than KRas G13D in a colorectal cancer model.
PMID: 25359494
Ref: Dual targeting of Angiopoetin-2 and VEGF potentiates effective vascular normalisation without inducing empty basement membrane sleeves in xenograft tumours.
PMID: 25562438
Ref: Efficacy of Cotargeting Angiopoietin-2 and the VEGF Pathway in the Adjuvant Postsurgical Setting for Early Breast, Colorectal, and Renal Cancers.
PMID: 27651308
Ref: Tumour-infiltrating neutrophils counteract anti-VEGF therapy in metastatic colorectal cancer.
PMID: 30377339