Primary Site >> Colorectal Cancer
Gene >> ANGPT1
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Ref: Differential expression of angiopoietin-1 and angiopoietin-2 in colon carcinoma. A possible mechanism for the initiation of angiogenesis. PMID: 11571726 |
Ref: Angiopoietin-1 inhibits tumour growth and ascites formation in a murine model of peritoneal carcinomatosis. PMID: 12402160 |
Ref: Hepatic expression of ANG2 RNA in metastatic colorectal cancer. PMID: 14768007 |
Ref: [Relationship of angiopoietins expression with microvessel density (MVD) in human colorectal tumors]. PMID: 16610088 Ref: Expression and prognostic significance of angiopoietin in colorectal carcinoma. PMID: 17066421 |
Ref: Angiopoietin-1 alters tumor growth by stabilizing blood vessels or by promoting angiogenesis. PMID: 19018775 |
Ref: Perioperative GMCSF limits the proangiogenic plasma protein changes associated with colorectal cancer resection. PMID: 18782657 Ref: Colorectal resection is associated with persistent proangiogenic plasma protein changes: postoperative plasma stimulates in vitro endothelial cell growth, migration, and invasion. PMID: 19474682 Ref: Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer. PMID: 19826039 Ref: [Assessment of the selected, late phase of angiogenesis factors' concentration in colorectal cancer patients]. PMID: 20120708 |
Ref: Minimally invasive colorectal resection for cancer is associated with a short-lived decrease in soluble Tie-2 receptor levels, which may transiently inhibit VEGF-mediated angiogenesis (via altered blood levels of free Ang-1 and Ang-2). PMID: 20354881 |
Ref: A human neutralizing antibody specific to Ang-2 inhibits ocular angiogenesis. PMID: 21851472 |
Ref: Recombinant canstatin inhibits angiopoietin-1-induced angiogenesis and lymphangiogenesis. PMID: 21823121 Ref: Characterization and significance of ACE2 and Mas receptor in human colon adenocarcinoma. PMID: 22048948 Ref: Genetic polymorphism in a VEGF-independent angiogenesis gene ANGPT1 and overall survival of colorectal cancer patients after surgical resection. PMID: 22496856 Ref: Plasma concentrations of angiopoietin-1, angiopoietin-2 and Tie-2 in colon cancer. PMID: 22728324 Ref: Grape seed proanthocyanidins inhibit colon cancer-induced angiogenesis through suppressing the expression of VEGF and Ang1. PMID: 23026853 |
Ref: Phase 1 study of trebananib (AMG 386), an angiogenesis targeting angiopoietin-1/2 antagonist, in Japanese patients with advanced solid tumors. PMID: 23124648 Ref: Antiangiogenic effects of ganetespib in colorectal cancer mediated through inhibition of HIF-1alpha and STAT-3. PMID: 23838996 |
Ref: Expression of angiogenic growth factors VEGF, bFGF and ANG1 in colon cancer after bevacizumab treatment in vitro: A potential self-regulating mechanism. PMID: 27840995 Ref: Expressions and Clinical Significances of Angiopoietin-1, Angiopoietin-2, and Tie-2 Receptor in Patients With Colorectal Cancer. PMID: 28289658 |