Primary Site >> Colorectal Cancer

Gene >> AMER1

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Ref: Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.
PMID: 17510365
Ref: Mutational analysis of WTX gene in Wnt/ beta-catenin pathway in gastric, colorectal, and hepatocellular carcinomas.
PMID: 18720004
Ref: Mutations in the WTX-gene are found in some high-grade microsatellite instable (MSI-H) colorectal cancers.
PMID: 20696052
Ref: Comprehensive molecular characterization of human colon and rectal cancer.
PMID: 22810696
Ref: Adenomatous polyposis coli (APC) membrane recruitment 3, a member of the APC membrane recruitment family of APC-binding proteins, is a positive regulator of Wnt-beta-catenin signalling.
PMID: 24251807
Ref: A novel WTX mutation in a female patient with osteopathia striata with cranial sclerosis and hepatoblastoma.
PMID: 24459086
Ref: Exome Sequencing Reveals AMER1 as a Frequently Mutated Gene in Colorectal Cancer.
PMID: 26071483
Ref: [Establishment of a colorectal cancer SW620 cell line stably over-expressing Wilm's tumor on X chromosome using a recombinant lentivirus vector].
PMID: 26277507
Ref: Adenoma development in familial adenomatous polyposis and MUTYH-associated polyposis: somatic landscape and driver genes.
PMID: 26414517
Ref: Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer.
PMID: 28002797
Ref: A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer.
PMID: 28551381
Ref: The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer.
PMID: 28675510
Ref: Aneuploidy of chromosome 8 and mutation of circulating tumor cells predict pathologic complete response in the treatment of locally advanced rectal cancer.
PMID: 30008877
Ref: Deep sequencing and pathway-focused analysis revealed multigene oncodriver signatures predicting survival outcomes in advanced colorectal cancer.
PMID: 30032163
Ref: Association Between Fusobacterium nucleatum, Pathway Mutation, and Patient Prognosis in Colorectal Cancer.
PMID: 30062471