Primary Site >> Colorectal Cancer
Gene >> ALCAM
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Ref: ALCAM/CD166 is overexpressed in colorectal carcinoma and correlates with shortened patient survival. PMID: 15509676 |
Ref: Cytoplasmic overexpression of ALCAM is prognostic of disease progression in breast cancer. PMID: 16484444 |
Ref: Phenotypic characterization of human colorectal cancer stem cells. PMID: 17548814 |
Ref: Activated leukocyte cell adhesion molecule: a new paradox in cancer. PMID: 18279810 Ref: Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity. PMID: 18765800 |
Ref: Age-related increase in colorectal cancer stem cells in macroscopically normal mucosa of patients with adenomas: a risk factor for colon cancer. PMID: 19010307 Ref: Phenotypic subpopulations of metastatic colon cancer stem cells: genomic analysis. PMID: 19451087 Ref: Combination of aging and dimethylhydrazine treatment causes an increase in cancer-stem cell population of rat colonic crypts. PMID: 19465005 Ref: Fumagillin inhibits colorectal cancer growth and metastasis in mice: in vivo and in vitro study of anti-angiogenesis. PMID: 19563408 Ref: Prognostic significance of the cancer stem cell markers CD133, CD44, and CD166 in colorectal cancer. PMID: 19626493 Ref: Elimination of Colon Cancer Stem-Like Cells by the Combination of Curcumin and FOLFOX. PMID: 19956394 |
Ref: ABCG5-positivity in tumor buds is an indicator of poor prognosis in node-negative colorectal cancer patients. PMID: 20135722 Ref: Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery. PMID: 20332776 Ref: Colon cancer stem cells: promise of targeted therapy. PMID: 20420952 Ref: Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer. PMID: 20606680 Ref: New-generation taxoid SB-T-1214 inhibits stem cell-related gene expression in 3D cancer spheroids induced by purified colon tumor-initiating cells. PMID: 20630067 Ref: A novel human recombinant single-chain antibody targeting CD166/ALCAM inhibits cancer cell invasion in vitro and in vivo tumour growth. PMID: 20635083 Ref: The Wnt/beta-catenin pathway regulates growth and maintenance of colonospheres. PMID: 20691072 Ref: Characterization of the intestinal cancer stem cell marker CD166 in the human and mouse gastrointestinal tract. PMID: 20826154 Ref: Molecular identification and targeting of colorectal cancer stem cells. PMID: 21311095 |
Ref: Difluorinated-curcumin (CDF): a novel curcumin analog is a potent inhibitor of colon cancer stem-like cells. PMID: 21161336 Ref: Colon cancer stem cells: implications in carcinogenesis. PMID: 21196254 Ref: Schlafen-3 decreases cancer stem cell marker expression and autocrine/juxtacrine signaling in FOLFOX-resistant colon cancer cells. PMID: 21596996 Ref: SNAIL regulates interleukin-8 expression, stem cell-like activity, and tumorigenicity of human colorectal carcinoma cells. PMID: 21640118 Ref: Mesenchymal stem cells promote formation of colorectal tumors in mice. PMID: 21699785 Ref: Combination of dasatinib and curcumin eliminates chemo-resistant colon cancer cells. PMID: 21774804 Ref: Common cancer stem cell gene variants predict colon cancer recurrence. PMID: 21918173 |
Ref: Effect of EpCAM, CD44, CD133 and CD166 expression on patient survival in tumours of the ampulla of Vater. PMID: 22130902 Ref: Cancer stem cell sorting from colorectal cancer cell lines by sedimentation field flow fractionation. PMID: 22236375 Ref: EGFR regulation of colon cancer stem-like cells during aging and in response to the colonic carcinogen dimethylhydrazine. PMID: 22281474 Ref: Activated leukocyte cell adhesion molecule (CD166)--its prognostic power for colorectal cancer patients. PMID: 22482754 Ref: Associations between markers of colorectal cancer stem cells and adenomas among ethnic groups. PMID: 22562538 Ref: A Pilot Study Assessing the Potential Role of non-CD133 Colorectal Cancer Stem Cells as Biomarkers. PMID: 22670157 Ref: CD24 can be used to isolate Lgr5+ putative colonic epithelial stem cells in mice. PMID: 22723265 Ref: CD133+, CD166+CD44+, and CD24+CD44+ phenotypes fail to reliably identify cell populations with cancer stem cell functional features in established human colorectal cancer cell lines. PMID: 23197865 |
Ref: Colorectal micropapillary carcinomas are associated with poor prognosis and enriched in markers of stem cells. PMID: 23060121 Ref: SSEA-3 as a novel amplifying cancer cell surface marker in colorectal cancers. PMID: 23175153 Ref: Kruppel-like factor 4 acts as an oncogene in colon cancer stem cell-enriched spheroid cells. PMID: 23418515 Ref: Elevated ALCAM shedding in colorectal cancer correlates with poor patient outcome. PMID: 23539446 Ref: CD49f-positive cell population efficiently enriches colon cancer-initiating cells. PMID: 23708747 Ref: Cytometric profiling of CD133+ cells in human colon carcinoma cell lines identifies a common core phenotype and cell type-specific mosaics. PMID: 23709346 Ref: Inhibition of the transcription factor Sp1 suppresses colon cancer stem cell growth and induces apoptosis in vitro and in nude mouse xenografts. PMID: 23877322 Ref: Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species. PMID: 23916687 Ref: Prognostic value of CD166 expression in cancers of the digestive system: a systematic review and meta-analysis. PMID: 23940674 Ref: Cancer stem cell gene profile as predictor of relapse in high risk stage II and stage III, radically resected colon cancer patients. PMID: 24023782 Ref: The association between CD166 detection rate and clinicopathologic parameters of patients with colorectal cancer. PMID: 24294471 |
Ref: Differential expression of CD133 based on microsatellite instability status in human colorectal cancer. PMID: 23065858 Ref: ALDH1 is an independent prognostic factor for patients with stages II-III rectal cancer after receiving radiochemotherapy. PMID: 24327017 Ref: Role of oncogenic K-Ras in cancer stem cell activation by aberrant Wnt/beta-catenin signaling. PMID: 24491301 Ref: P21 and CD166 as predictive markers of poor response and outcome after fluorouracil-based chemoradiotherapy for the patients with rectal cancer. PMID: 24708484 Ref: Establishment of highly tumorigenic human colorectal cancer cell line (CR4) with properties of putative cancer stem cells. PMID: 24921652 Ref: CD133/CD166/Ki-67 triple immunofluorescence assessment for putative cancer stem cells in colon carcinoma. PMID: 24949608 Ref: Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture. PMID: 25075203 Ref: Enhanced immunoPET of ALCAM-positive colorectal carcinoma using site-specific (6)(4)Cu-DOTA conjugation. PMID: 25095796 Ref: Colon cancer: cancer stem cells markers, drug resistance and treatment. PMID: 25458789 Ref: Stem cells, colorectal cancer and cancer stem cell markers correlations. PMID: 25729599 |
Ref: Surface profiles of live colorectal cancer cells and tumor infiltrating lymphocytes from surgical samples correspond to prognostic categories. PMID: 25445327 Ref: Serum CD166: a novel hepatocellular carcinoma tumor marker. PMID: 25562819 Ref: LGR5 rs17109924 is a predictive genetic biomarker for time to recurrence in patients with colon cancer treated with 5-fluorouracil-based adjuvant chemotherapy. PMID: 25665511 Ref: The effects of folic acid on global DNA methylation and colonosphere formation in colon cancer cell lines. PMID: 25804133 Ref: The Proportion of ALDEFLUOR-Positive Cancer Stem Cells Changes with Cell Culture Density Due to the Expression of Different ALDH Isoforms. PMID: 28280782 |
Ref: Isolation of colorectal cancer stem-like cells. PMID: 25535115 Ref: Role of cancer stem cells in racial disparity in colorectal cancer. PMID: 26990997 Ref: Circulating tumor cells exhibit stem cell characteristics in an orthotopic mouse model of colorectal cancer. PMID: 27029058 Ref: KRAS mutation associated with CD44/CD166 immunoexpression as predictors of worse outcome in metastatic colon cancer. PMID: 27062566 Ref: Associations between markers of colorectal cancer stem cells, mutation, microRNA and the clinical features of ulcerative colitis. PMID: 27153478 Ref: Association of CD166 expression with clinicopathologic characteristics of colorectal cancer. PMID: 27386070 Ref: Twist1-induced epithelial-mesenchymal transition according to microsatellite instability status in colon cancer cells. PMID: 27494849 Ref: Characterization of cancer stem cells from different grades of human colorectal cancer. PMID: 27507615 Ref: IL-13/STAT6 signaling plays a critical role in the epithelial-mesenchymal transition of colorectal cancer cells. PMID: 27533463 Ref: Acquisition of anticancer drug resistance is partially associated with cancer stemness in human colon cancer cells. PMID: 27748801 |
Ref: Role of Stem Cells in Colorectal Cancer Progression and Prognostic and Predictive Characteristics of Stem Cell Markers in Colorectal Cancer. PMID: 27593447 Ref: Identification of High-Risk Aberrant Crypt Foci and Mucin-Depleted Foci in the Human Colon With Study of Colon Cancer Stem Cell Markers. PMID: 27789195 Ref: Clinicopathologic profile, immunophenotype, and genotype of CD274 (PD-L1)-positive colorectal carcinomas. PMID: 27813511 Ref: Six1 promotes colorectal cancer growth and metastasis by stimulating angiogenesis and recruiting tumor-associated macrophages. PMID: 28199476 Ref: The Identifications and Clinical Implications of Cancer Stem Cells in Colorectal Cancer. PMID: 28237538 Ref: Meta-analysis indicating that high ALCAM expression predicts poor prognosis in colorectal cancer. PMID: 28537909 Ref: Clinicopathological, prognostic and predictive value of CD166 expression in colorectal cancer: a meta-analysis. PMID: 28969077 Ref: Roles of microRNAs and RNA-Binding Proteins in the Regulation of Colorectal Cancer Stem Cells. PMID: 29064439 Ref: Histopathological and genotypic characterization of metastatic colorectal carcinoma with PD-L1 (CD274)-expression: Possible roles of tumour micro environmental factors for CD274 expression. PMID: 29085667 Ref: Long intergenic non-protein-coding RNA 1567 (LINC01567) acts as a "sponge" against microRNA-93 in regulating the proliferation and tumorigenesis of human colon cancer stem cells. PMID: 29110645 |
Ref: Overexpression of HOXA4 and HOXA9 genes promotes self-renewal and contributes to colon cancer stem cell overpopulation. PMID: 28464221 Ref: Lgr5+CD44+EpCAM+ Strictly Defines Cancer Stem Cells in Human Colorectal Cancer. PMID: 29627827 Ref: Hotspot KRAS exon 2 mutations in CD166 positive colorectal cancer and colorectal adenoma cells. PMID: 29755662 Ref: ALDH1A3 upregulation and spontaneous metastasis formation is associated with acquired chemoresistance in colorectal cancer cells. PMID: 30143021 |