Primary Site >> Colorectal Cancer

Gene >> AKR1C1

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Ref: Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells.
PMID: 8573067
Ref: Cytoplasmically sequestered wild-type p53 protein in neuroblastoma is relocated to the nucleus by a C-terminal peptide.
PMID: 8986786
Ref: Coordinate changes in expression of protective genes in drug-resistant cells.
PMID: 9679555
Ref: Sequence of the cDNA of a human dihydrodiol dehydrogenase isoform (AKR1C2) and tissue distribution of its mRNA.
PMID: 9716498
Ref: Isoform-specific induction of a human aldo-keto reductase by polycyclic aromatic hydrocarbons (PAHs), electrophiles, and oxidative stress: implications for the alternative pathway of PAH activation catalyzed by human dihydrodiol dehydrogenase.
PMID: 9973208
Ref: Transcriptional regulation of aldo-keto reductase 1C1 in HT29 human colon cancer cells resistant to methotrexate: role in the cell cycle and apoptosis.
PMID: 17945194
Ref: [Effect of tBHQ and sulforaphane on Nrf2-ARE signaling pathway of Caco2 cells].
PMID: 20175231
Ref: Inhibitors of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1).
PMID: 21050889
Ref: Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29.
PMID: 21215737
Ref: Methylation of the KEAP1 gene promoter region in human colorectal cancer.
PMID: 22325485
Ref: Enhanced 4-hydroxynonenal resistance in KEAP1 silenced human colon cancer cells.
PMID: 23766854