Primary Site >> Colorectal Cancer
Gene >> AKR1B1
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Ref: Adriamycin-induced resistance to natural killer (NK)-mediated cytotoxicity. PMID: 2786743 |
Ref: Aldose reductase regulates growth factor-induced cyclooxygenase-2 expression and prostaglandin E2 production in human colon cancer cells. PMID: 17018629 |
Ref: Post-transcriptional regulation of P-glycoprotein expression in cancer cell lines. PMID: 17579122 |
Ref: Pharmacokinetic profile of the microtubule stabilizer patupilone in tumor-bearing rodents and comparison of anti-cancer activity with other MTS in vitro and in vivo. PMID: 18301895 |
Ref: Inhibition of aldose reductase prevents growth factor-induced G1-S phase transition through the AKT/phosphoinositide 3-kinase/E2F-1 pathway in human colon cancer cells. PMID: 20354121 Ref: [Downregulation of AKR1B10 gene expression in colorectal cancer]. PMID: 20586184 |
Ref: Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29. PMID: 21215737 Ref: ALDOSE REDUCTASE: New Insights for an Old Enzyme. PMID: 21547010 Ref: Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid. PMID: 21561086 Ref: Inhibition of aldose reductase prevents colon cancer metastasis. PMID: 21642355 |
Ref: Aldose reductase inhibition prevents colon cancer growth by restoring phosphatase and tensin homolog through modulation of miR-21 and FOXO3a. PMID: 22978663 Ref: Preventive cancer stem cell-based vaccination reduces liver metastasis development in a rat colon carcinoma syngeneic model. PMID: 23193035 Ref: Aldose reductase inhibition enhances TRAIL-induced human colon cancer cell apoptosis through AKT/FOXO3a-dependent upregulation of death receptors. PMID: 23732517 Ref: Aldose reductase inhibition suppresses colon cancer cell viability by modulating microRNA-21 mediated programmed cell death 4 (PDCD4) expression. PMID: 23827854 |
Ref: Identification of novel hypermethylated genes and demethylating effect of vincristine in colorectal cancer. PMID: 24393480 Ref: Sorbitol dehydrogenase overexpression and other aspects of dysregulated protein expression in human precancerous colorectal neoplasms: a quantitative proteomics study. PMID: 24567419 |
Ref: Expression of AKR1C3 and CNN3 as markers for detection of lymph node metastases in colorectal cancer. PMID: 24934327 Ref: Epigenetics override pro-inflammatory PTGS transcriptomic signature towards selective hyperactivation of PGE2 in colorectal cancer. PMID: 26207152 |
Ref: Discovery and Validation of Hypermethylated Markers for Colorectal Cancer. PMID: 27493446 Ref: Trends in quality of screening colonoscopy in Austria. PMID: 27576182 |
Ref: Opposing roles of the aldo-keto reductases AKR1B1 and AKR1B10 in colorectal cancer. PMID: 28929377 |
Ref: Polyol Pathway Links Glucose Metabolism to the Aggressiveness of Cancer Cells. PMID: 29343522 Ref: Diagnostic Yield and Miss Rate of EndoRings in an Organized Colorectal Cancer Screening Program: the SMART (Study Methodology for ADR-Related Technology) Trial. PMID: 30365984 |