Primary Site >> Colorectal Cancer

Gene >> AGR2

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Ref: Differential expression in normal-adenoma-carcinoma sequence suggests complex molecular carcinogenesis in colon.
PMID: 16969489
Ref: SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells.
PMID: 19786015
Ref: Genome-wide molecular characterization of mucinous colorectal adenocarcinoma using cDNA microarray analysis.
PMID: 21206979
Ref: In vitro induction of anterior gradient-2-specific cytotoxic T lymphocytes by dendritic cells transduced with recombinant adenoviruses as a potential therapy for colorectal cancer.
PMID: 22089087
Ref: Identification of novel HLA-A*0201-restricted epitopes from anterior gradient-2 as a tumor-associated antigen against colorectal cancer.
PMID: 22231555
Ref: Evaluation of the adenocarcinoma-associated gene AGR2 and the intestinal stem cell marker LGR5 as biomarkers in colorectal cancer.
PMID: 22605983
Ref: A study of gene expression markers for predictive significance for bevacizumab benefit in patients with metastatic colon cancer: a translational research study of the Hellenic Cooperative Oncology Group (HeCOG).
PMID: 24555920
Ref: Loss of anterior gradient-2 expression is an independent prognostic factor in colorectal carcinomas.
PMID: 24794000
Ref: mRNA expression profiles in circulating tumor cells of metastatic colorectal cancer patients.
PMID: 25655581
Ref: Proteoglycans as potential microenvironmental biomarkers for colon cancer.
PMID: 25715761
Ref: SERPINI1 regulates epithelial-mesenchymal transition in an orthotopic implantation model of colorectal cancer.
PMID: 26892864
Ref: Secreted AGR2 promotes invasion of colorectal cancer cells via Wnt11-mediated non-canonical Wnt signaling.
PMID: 29427622
Ref: Anterior gradient 2 as a supervisory marker for tumor vessel normalization induced by anti-angiogenic treatment.
PMID: 30127899