Primary Site >> Colorectal Cancer
Gene >> ADIPOQ
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Ref: Production of adiponectin, an anti-inflammatory protein, in mesenteric adipose tissue in Crohn's disease. PMID: 15888786 Ref: Low plasma adiponectin levels and risk of colorectal cancer in men: a prospective study. PMID: 16288122 |
Ref: Adiponectin, ghrelin, and leptin in cancer cachexia in breast and colon cancer patients. PMID: 16411208 Ref: Serum adiponectin is not associated with risk of colorectal cancer. PMID: 16492937 Ref: Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells. PMID: 16529829 Ref: Profiling adipocytokine secretion from creeping fat in Crohn's disease. PMID: 16775490 |
Ref: Serum adiponectin concentrations and tissue expression of adiponectin receptors are reduced in patients with prostate cancer: a case control study. PMID: 17301264 Ref: Prognostic significance of adiponectin levels in non-metastatic colorectal cancer. PMID: 17348431 Ref: Adiponectin in relation to malignancies: a review of existing basic research and clinical evidence. PMID: 18265479 |
Ref: Assessing the potential usefulness of IGF-related peptides and adiponectin for predicting disease risk. PMID: 17928251 Ref: Tumor markers in staging and prognosis of colorectal carcinoma. PMID: 18237252 Ref: Adiponectin receptor expression is elevated in colorectal carcinomas but not in gastrointestinal stromal tumors. PMID: 18310295 Ref: Suppressive effects of nobiletin on hyperleptinemia and colitis-related colon carcinogenesis in male ICR mice. PMID: 18375960 Ref: Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition. PMID: 18676419 Ref: Expression of adiponectin receptors, AdipoR1 and AdipoR2, in normal colon epithelium and colon cancer tissue. PMID: 18695895 Ref: Variants of the adiponectin (ADIPOQ) and adiponectin receptor 1 (ADIPOR1) genes and colorectal cancer risk. PMID: 18827209 Ref: Adiponectin deficiency enhances colorectal carcinogenesis and liver tumor formation induced by azoxymethane in mice. PMID: 19030198 Ref: The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-activated protein kinase. PMID: 19138981 |
Ref: Association of visceral fat accumulation and adiponectin levels with colorectal neoplasia. PMID: 18716871 Ref: Serum leptin, adiponectin, and resistin concentration in colorectal adenoma and carcinoma (CC) patients. PMID: 18979105 Ref: Association of visceral fat accumulation and plasma adiponectin with rectal dysplastic aberrant crypt foci in a clinical population. PMID: 19018760 Ref: Elevated circulating adiponectin and elevated insulin sensitivity in adiponectin transgenic mice are not associated with reduced susceptibility to colon carcinogenesis. PMID: 19123482 Ref: Adiponectin inhibits colorectal cancer cell growth through the AMPK/mTOR pathway. PMID: 19148467 Ref: Common variation at the adiponectin locus is not associated with colorectal cancer risk in the UK. PMID: 19264763 Ref: Genetic variation in adipokine genes and risk of colorectal cancer. PMID: 19273568 Ref: Preoperative plasma adiponectin level is a risk factor for postoperative infection following colorectal cancer surgery. PMID: 19394964 Ref: The signal pathways in azoxymethane-induced colon cancer and preventive implications. PMID: 19502780 Ref: Adiponectin in obesity-associated colon cancer and its preventive implications: comment on "Association of visceral fat accumulation and adiponectin levels with colorectal neoplasia". PMID: 19513834 Ref: Adiponectin is not effective against AOM-induced colon cancer but more evidence is required for its role in obesity-associated colon cancer: comment on the study by Ealey and Archer (2009). PMID: 19544561 Ref: Prognostic significance of serum adipokine levels in colorectal cancer patients. PMID: 19661351 Ref: Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancer. PMID: 19760027 Ref: Metabolic syndrome and risk of subsequent colorectal cancer. PMID: 19891012 Ref: Adiponectin immunohistochemical expression in colorectal cancer and its correlation with histological grade and tumour microvessel density. PMID: 19900101 Ref: Reduced expression of the AdipoR1 gene is correlated with venous invasion in colorectal cancer. PMID: 21475865 |
Ref: Evidence for the contribution of insulin resistance to the development of cachexia in tumor-bearing mice. PMID: 19634137 Ref: Association between adiponectin, resistin, insulin resistance, and colorectal tumors. PMID: 19888587 Ref: Decreased levels of plasma adiponectin associated with increased risk of colorectal cancer. PMID: 20222170 Ref: Adipocytokines as new promising markers of colorectal tumors: adiponectin for colorectal adenoma, and resistin and visfatin for colorectal cancer. PMID: 20331631 Ref: Adiponectin and resistin: biomarker for colorectal cancer? PMID: 20393737 Ref: Pitavastatin inhibits azoxymethane-induced colonic preneoplastic lesions in C57BL/KsJ-db/db obese mice. PMID: 20398056 Ref: Serum adiponectin, leptin, C-peptide, homocysteine, and colorectal adenoma recurrence in the Polyp Prevention Trial. PMID: 20501764 Ref: Interaction between adiponectin and leptin influences the risk of colorectal adenoma. PMID: 20516125 Ref: Adipokine regulation of colon cancer: adiponectin attenuates interleukin-6-induced colon carcinoma cell proliferation via STAT-3. PMID: 20564347 Ref: Genetic variation in adiponectin (ADIPOQ) and the type 1 receptor (ADIPOR1), obesity and prostate cancer in African Americans. PMID: 20697428 Ref: The relationship among acute-phase response proteins, cytokines and hormones in cachectic patients with colon cancer. PMID: 20920199 Ref: Association of LEP and ADIPOQ common variants with colorectal cancer in Mexican patients. PMID: 21263187 Ref: Adiponectin and adiponectin receptor in relation to colorectal cancer progression. PMID: 21351255 |
Ref: Bayesian analysis of genetic interactions in case-control studies, with application to adiponectin genes and colorectal cancer risk. PMID: 20846215 Ref: Association of angiopoietin-2, C-reactive protein and markers of obesity and insulin resistance with survival outcome in colorectal cancer. PMID: 21081932 Ref: Parameters of biological activity in colorectal cancer. PMID: 21273626 Ref: Adiponectin supports cell survival in glucose deprivation through enhancement of autophagic response in colorectal cancer cells. PMID: 21299716 Ref: Loss of adiponectin promotes intestinal carcinogenesis in Min and wild-type mice. PMID: 21334339 Ref: Energy balance modulates colon tumor growth: Interactive roles of insulin and estrogen. PMID: 21480390 Ref: Serum adiponectin levels and tissue expression of adiponectin receptors are associated with risk, stage, and grade of colorectal cancer. PMID: 21632074 Ref: Associations of single nucleotide polymorphisms in the adiponectin gene with adiponectin levels and cardio-metabolic risk factors in patients with cancer. PMID: 21694446 Ref: Effects of genetic variations in the adiponectin pathway genes on the risk of colorectal cancer in the Chinese population. PMID: 21749709 Ref: Meta-analysis: circulating adiponectin levels and risk of colorectal cancer and adenoma. PMID: 21791018 Ref: Adiponectin gene and risk of colorectal cancer. PMID: 21829206 Ref: Probiotics modulate intestinal expression of nuclear receptor and provide counter-regulatory signals to inflammation-driven adipose tissue activation. PMID: 21829567 Ref: Early lesion formation in colorectal carcinogenesis is associated with adiponectin status whereas neoplastic lesions are associated with diet and sex in C57BL/6J mice. PMID: 21958077 Ref: Low-dose dietary resveratrol has differential effects on colorectal tumorigenesis in adiponectin knockout and wild-type mice. PMID: 21958119 Ref: Interactions between genetic variants in the adiponectin, adiponectin receptor 1 and environmental factors on the risk of colorectal cancer. PMID: 22087284 Ref: Adiposity factors are not related to the presence of colorectal adenomas. PMID: 22162929 Ref: Comparison of adiponectin concentration between pancreatic cancer and colorectal cancer. PMID: 22811857 |
Ref: The relationship among acute-phase responce proteins, cytokines, and hormones in various gastrointestinal cancer types patients with cachectic. PMID: 21803781 Ref: Adiponectin levels in patients with colorectal cancer and adenoma: a meta-analysis. PMID: 21960184 Ref: Preventive effects of curcumin on the development of azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/db obese mice. PMID: 22172229 Ref: Novel multiplex method to assess insulin, leptin and adiponectin regulation of inflammatory cytokines associated with colon cancer. PMID: 22193626 Ref: Adiponectin deficiency: role in chronic inflammation induced colon cancer. PMID: 22198319 Ref: [Obesity and colorectal cancer]. PMID: 22289950 Ref: Pathophysiological role of hormones and cytokines in cancer cachexia. PMID: 22323858 Ref: Total and high-molecular weight adiponectin and risk of colorectal cancer: the European Prospective Investigation into Cancer and Nutrition Study. PMID: 22431719 Ref: Associations between adiponectin and two different cancers: breast and colon. PMID: 22502709 Ref: Genetic variants in IGF-I, IGF-II, IGFBP-3, and adiponectin genes and colon cancer risk in African Americans and Whites. PMID: 22565227 Ref: Pre-diagnostic levels of adiponectin and soluble vascular cell adhesion molecule-1 are associated with colorectal cancer risk. PMID: 22719189 Ref: The adiponectin gene, ADIPOQ, and genetic susceptibility to colon cancer. PMID: 22740876 Ref: Adiponectin receptor 2 is negatively associated with lymph node metastasis of colorectal cancer. PMID: 22740988 Ref: Association of plasma total and high-molecular-weight adiponectin with risk of colorectal cancer: an observational study in Chinese male. PMID: 22752603 Ref: PAQR3 plays a suppressive role in the tumorigenesis of colorectal cancers. PMID: 22828136 Ref: Estrogen in obesity-associated colon cancer: friend or foe? Protecting postmenopausal women but promoting late-stage colon cancer. PMID: 23011535 Ref: Obesity-driven inflammation and colorectal cancer. PMID: 23033947 Ref: Cytosolic malic enzyme 1 (ME1) mediates high fat diet-induced adiposity, endocrine profile, and gastrointestinal tract proliferation-associated biomarkers in male mice. PMID: 23056418 Ref: Changed adipocytokine concentrations in colorectal tumor patients and morbidly obese patients compared to healthy controls. PMID: 23173608 Ref: Serum adiponectin level and different kinds of cancer: a review of recent evidence. PMID: 23213569 Ref: The relationship between nonalcoholic fatty liver disease and colorectal cancer: the future challenges and outcomes of the metabolic syndrome. PMID: 23304464 Ref: Role of adiponectin and its receptors in cancer. PMID: 23691481 |
Ref: Salutary effects of adiponectin on colon cancer: in vivo and in vitro studies in mice. PMID: 22735569 Ref: Decreased systemic IGF-1 in response to calorie restriction modulates murine tumor cell growth, nuclear factor-kappaB activation, and inflammation-related gene expression. PMID: 22778026 Ref: Adiponectin: a relevant player in obesity-related colorectal cancer? PMID: 22851665 Ref: Three adiponectin rs1501299G/T, rs822395A/C, and rs822396A/G polymorphisms and risk of cancer development: a meta-analysis. PMID: 23225349 Ref: Mucus and adiponectin deficiency: role in chronic inflammation-induced colon cancer. PMID: 23474825 Ref: Effects of a 12-week home-based exercise program on the level of physical activity, insulin, and cytokines in colorectal cancer survivors: a pilot study. PMID: 23636649 Ref: Linking obesity to colorectal cancer: recent insights into plausible biological mechanisms. PMID: 23743611 Ref: Adipocytokine levels of colon cancer patients before and after treatment. PMID: 23822624 Ref: Gene Polymorphisms of ADIPOQ +45T>G, UCP2 -866G>A, and FABP2 Ala54Thr on the Risk of Colorectal Cancer: A Matched Case-Control Study. PMID: 23826253 Ref: Meta-analysis of adiponectin polymorphisms and colorectal cancer risk. PMID: 23869187 Ref: Plasma adiponectin and soluble leptin receptor and risk of colorectal cancer: a prospective study. PMID: 23872505 Ref: Reduction of intestinal polyp formation in min mice fed a high-fat diet with aloe vera gel extract. PMID: 23992016 Ref: omega3-PUFAs exert anti-inflammatory activity in visceral adipocytes from colorectal cancer patients. PMID: 24116229 Ref: Adiponectin and metformin additively attenuate IL1beta-induced malignant potential of colon cancer. PMID: 24157941 Ref: Colon epithelial proliferation and carcinogenesis in diet-induced obesity. PMID: 24251703 Ref: The Association between Polymorphismsin Insulin and Obesity Related Genesand Risk of Colorectal Cancer. PMID: 25250132 |
Ref: An updated meta-analysis of the association between ADIPOQ rs2241766 polymorphism and colorectal cancer. PMID: 24293390 Ref: Adiponectin as a routine clinical biomarker. PMID: 24417951 Ref: Obesity related adipokines and colorectal cancer: a review and meta-analysis. PMID: 24528064 Ref: Globular adiponectin and its downstream target genes are up-regulated locally in human colorectal tumors: ex vivo and in vitro studies. PMID: 24636346 Ref: [Association between adiponectin rs2241766, rs1501299 polymorphisms and the risk of colorectal cancer]. PMID: 24739564 Ref: Biomarker patterns of inflammatory and metabolic pathways are associated with risk of colorectal cancer: results from the European Prospective Investigation into Cancer and Nutrition (EPIC). PMID: 24791703 Ref: Association between obesity-related adipokines and colorectal cancer: a case-control study and meta-analysis. PMID: 24976730 Ref: Clinical significance of adiponectin expression in colon cancer patients. PMID: 25022390 Ref: The influence of nutritional status and disease on adiponectin and TNF-alpha; levels in colorectal cancer patients. PMID: 25137273 Ref: Association between chemotherapy and plasma adipokines in patients with colorectal cancer. PMID: 25149999 Ref: Adipokines do not mediate the association of obesity and colorectal adenoma. PMID: 25197277 Ref: Carnosic acid suppresses colon tumor formation in association with antiadipogenic activity. PMID: 25204550 Ref: Involvement of adiponectin in early stage of colorectal carcinogenesis. PMID: 25370174 Ref: Association of adiponectin receptor (Adipo-R1/-R2) expression and colorectal cancer. PMID: 25422229 Ref: Associations between variants on ADIPOQ and ADIPOR1 with colorectal cancer risk: a Chinese case-control study and updated meta-analysis. PMID: 25516230 |
Ref: Genetic variants of adiponectin and risk of colorectal cancer. PMID: 25431318 Ref: Association between adiponectin polymorphisms and the risk of colorectal cancer. PMID: 25489716 Ref: The relationship between serum adiponectin and resistin levels, insulin resistance and colorectal adenomas. PMID: 25698266 Ref: Association between plasma adiponectin levels and colorectal cancer risk in women. PMID: 25941065 Ref: The Inhibitory Efficacy of Methylseleninic Acid Against Colon Cancer Xenografts in C57BL/6 Mice. PMID: 26011019 Ref: Obesity and Obese-related Chronic Low-grade Inflammation in Promotion of Colorectal Cancer Development. PMID: 26028066 Ref: Gene polymorphisms related to insulin resistance and gene-environment interaction in colorectal cancer risk. PMID: 26203767 Ref: AdipoRon: a possible drug for colorectal cancer prevention? PMID: 26282004 Ref: Adiponectin Gene Polymorphisms are Associated with Increased Risk of Colorectal Cancer. PMID: 26329379 Ref: Gene-gene interaction analysis identifies a new genetic risk factor for colorectal cancer. PMID: 26362652 Ref: Prediagnostic Plasma Adiponectin and Survival among Patients with Colorectal Cancer. PMID: 26382604 Ref: Obesity promotes colonic stem cell expansion during cancer initiation. PMID: 26455770 Ref: Circulating Levels of Adipocytokines as Potential Biomarkers for Early Detection of Colorectal Carcinoma in Egyptian Patients. PMID: 26514469 Ref: [Serum adipokines and their receptors in endometrial and colon cancer patients: relationship with tumor invasion and metastasis]. PMID: 26571833 |
Ref: Comparison of plasma levels of obesity-related biomarkers among Japanese populations in Tokyo, Japan, Sao Paulo, Brazil, and Hawaii, USA. PMID: 25714650 Ref: Peritumoral adipose tissue as a source of inflammatory and angiogenic factors in colorectal cancer. PMID: 26493186 Ref: Prediagnosis Plasma Adiponectin in Relation to Colorectal Cancer Risk According to KRAS Mutation Status. PMID: 26598515 Ref: Inflammation and chemerin in colorectal cancer. PMID: 26628300 Ref: Cardiopulmonary fitness, adiponectin, chemerin associated fasting insulin level in colorectal cancer patients. PMID: 26847448 Ref: Adiponectin induces CXCL1 secretion from cancer cells and promotes tumor angiogenesis by inducing stromal fibroblast senescence. PMID: 27092462 Ref: Alteration of Leptin and Adiponectin in Multistep Colorectal Tumorigenesis. PMID: 27221946 Ref: Perioperative Adiponectin Measurement is Useful for Prediction of Postoperative Infection in Patients with Colorectal Cancer. PMID: 27364509 Ref: Role of omentin and chemerin in metabolic syndrome and tumor diseases. PMID: 27516571 Ref: Association of adiponectin receptor 1 gene - 106 C > T variant with susceptibility to colorectal cancer. PMID: 27617220 Ref: Association of IGFBP-6 Expression with Metabolic Syndrome and Adiponectin and IGF-IR Receptor Levels in Colorectal Cancer. PMID: 27644646 |
Ref: Adiponectin and colorectal cancer. PMID: 27061803 Ref: A population-specific correlation between ADIPOQ rs2241766 and rs 1501299 and colorectal cancer risk: a meta-analysis for debate. PMID: 27704292 Ref: Dietary selenium protects adiponectin knockout mice against chronic inflammation induced colon cancer. PMID: 28045589 Ref: Genome-wide analysis identifies colonic genes differentially associated with serum leptin and insulin concentrations in C57BL/6J mice fed a high-fat diet. PMID: 28170448 Ref: Adiponectin as a Potential Therapeutic Target for Prostate Cancer. PMID: 28183249 Ref: Association of ADIPOQ and ADIPOR variants with risk of colorectal cancer: A meta-analysis. PMID: 28397042 Ref: Chemotherapy and plasma adipokines level in patients with colorectal cancer. PMID: 28402255 Ref: Adiponectin and Intelectin-1: Important Adipokine Players in Obesity-Related Colorectal Carcinogenesis. PMID: 28422056 Ref: Lactobacillus casei Zhang and vitamin K2 prevent intestinal tumorigenesis in mice via adiponectin-elevated different signaling pathways. PMID: 28445967 Ref: ADIPOQ rs266729 G/C gene polymorphism and plasmatic adipocytokines connect metabolic syndrome to colorectal cancer. PMID: 28529612 Ref: Genetic variation in the ADIPOQ gene, adiponectin concentrations and risk of colorectal cancer: a Mendelian Randomization analysis using data from three large cohort studies. PMID: 28550647 Ref: MicroRNA-mediated MMP Regulation: Current Diagnostic and Therapeutic Strategies for Metabolic Syndrome. PMID: 28685672 Ref: Effect of home-based exercise intervention on fasting insulin and Adipocytokines in colorectal cancer survivors: a randomized controlled trial. PMID: 28987237 Ref: Morphological and Functional Changes in the Peritumoral Adipose Tissue of Colorectal Cancer Patients. PMID: 29086519 |
Ref: A prospective, multicenter pilot study to investigate the feasibility and safety of a 1-year controlled exercise training after adjuvant chemotherapy in colorectal cancer patients. PMID: 29168033 Ref: Adiponectin and colon cancer: evidence for inhibitory effects on viability and migration of human colorectal cell lines. PMID: 29446048 Ref: The role of metabolic syndrome variant in the malignant tumors progression. PMID: 29699953 Ref: Circulating and Adipose Tissue mRNA Levels of Zinc-alpha2-Glycoprotein, Leptin, High-Molecular-Weight Adiponectin, and Tumor Necrosis Factor-Alpha in Colorectal Cancer Patients With or Without Obesity. PMID: 29755407 Ref: Upregulation of the adipokine genes ADIPOR1 and SPP1 is related to poor survival outcomes in colorectal cancer. PMID: 29761507 Ref: Low circulating total adiponectin, especially its non-high-molecular weight fraction, represents a promising risk factor for colorectal cancer: a meta-analysis. PMID: 29765231 Ref: [Adiponectin inhibits proliferation and induces apoptosis in colorectal cancer HCT116 cells]. PMID: 29773108 Ref: Polymorphisms in genes related to inflammation and obesity and colorectal adenoma risk. PMID: 29802748 Ref: Metformin in cancer. PMID: 29807101 Ref: Sex-Specific Association between Family History of Diabetes and Risk of Colorectal Cancer: Two Prospective Cohort Studies. PMID: 29991578 Ref: Submucosal fat accumulation in human colorectal tissue and its association with abdominal obesity and insulin resistance. PMID: 30228895 Ref: Leptin gene variants and colorectal cancer risk: Sex-specific associations. PMID: 30379922 |