Primary Site >> Colorectal Cancer

Gene >> ACLY

  • 1994
  • 2010
  • 2013
  • 2015
Ref: Early changes in energy metabolism in rats exposed to an acute level of deoxycholate and fed a Nigerian-like diet.
PMID: 7979171
 Ref: The phosphoinositide 3-kinase inhibitor PI-103 downregulates choline kinase alpha leading to phosphocholine and total choline decrease detected by magnetic resonance spectroscopy.
PMID: 20551061
 Ref: Inhibition of ATP citrate lyase induces an anticancer effect via reactive oxygen species: AMPK as a predictive biomarker for therapeutic impact.
PMID: 23506848
Ref: ATP citrate lyase mediates resistance of colorectal cancer cells to SN38.
PMID: 24132143
 Ref: ATP citrate lyase (ACLY): a promising target for cancer prevention and treatment.
PMID: 25537655
Ref: Functional polymorphisms of ATP citrate lyase gene predicts clinical outcome of patients with advanced colorectal cancer.
PMID: 25890184