Primary Site >> Colorectal Cancer

Gene >> ABR

  • 2007
  • 2009
  • 2012
  • 2014
Ref: Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element.
PMID: 17145773
Ref: Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42.
PMID: 17599059
Ref: Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration.
PMID: 19151759
Ref: Structural basis for the recognition of Asef by adenomatous polyposis coli.
PMID: 21788986
Ref: RNA-seq reveals determinants for irinotecan sensitivity/resistance in colorectal cancer cell lines.
PMID: 24966994