Primary Site >> Stomach Cancer

Gene >> ABCC2

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Ref: Pharmacogenetics of stomach cancer.
PMID: 12914384
Ref: Reversal of different drug-resistant phenotypes by an autocatalytic multitarget multiribozyme directed against the transcripts of the ABC transporters MDR1/P-gp, MRP2, and BCRP.
PMID: 15771954
Ref: The overexpression of multidrug resistance-associated proteins and gankyrin contribute to arsenic trioxide resistance in liver and gastric cancer cells.
PMID: 19513507
Ref: The effect of radixin knockdown on the expression and efflux function of MRP2 in SGC-7901 cells.
PMID: 22469515
Ref: Loss of Runt-related transcription factor 3 induces resistance to 5-fluorouracil and cisplatin in hepatocellular carcinoma.
PMID: 26985715
Ref: ABCC2-24C > T polymorphism is associated with the response to platinum/5-Fu-based neoadjuvant chemotherapy and better clinical outcomes in advanced gastric cancer patients.
PMID: 27487151
Ref: DS-8201a, a new HER2-targeting antibody-drug conjugate incorporating a novel DNA topoisomerase I inhibitor, overcomes HER2-positive gastric cancer T-DM1 resistance.
PMID: 28677116
Ref: Combination of TNM staging and pathway based risk score models in patients with gastric cancer.
PMID: 29231991
Ref: Conditioned medium mimicking the tumor microenvironment augments chemotherapeutic resistance via ataxiatelangiectasia mutated and nuclear factorkappaB pathways in gastric cancer cells.
PMID: 30106453
Ref: Y-box binding protein-1 and STAT3 independently regulate ATP-binding cassette transporters in the chemoresistance of gastric cancer cells.
PMID: 30221675