Primary Site >> Colorectal Cancer
Gene >> ABCC1
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Ref: Heterogeneity of mucin gene expression in normal and neoplastic tissues. PMID: 7678777 |
Ref: The LRP gene encoding a major vault protein associated with drug resistance maps proximal to MRP on chromosome 16: evidence that chromosome breakage plays a key role in MRP or LRP gene amplification. PMID: 7671223 |
Ref: Effects of chronic ethacrynic acid exposure on glutathione conjugation and MRP expression in human colon tumor cells. PMID: 8630053 Ref: Frequent coordinated overexpression of the MRP/GS-X pump and gamma-glutamylcysteine synthetase genes in human colorectal cancers. PMID: 8705999 |
Ref: Tumor necrosis factor-alpha and expression of the multidrug resistance-associated genes LRP and MRP. PMID: 9182980 Ref: Human canalicular multispecific organic anion transporter (cMOAT) is expressed in human lung, gastric, and colorectal cancer cells. PMID: 9398612 |
Ref: Frequent coexpression of MRP/GS-X pump and gamma-glutamylcysteine synthetase mRNA in drug-resistant cells, untreated tumor cells, and normal mouse tissues. PMID: 9515571 Ref: Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C. PMID: 9865745 |
Ref: Expression of multidrug resistance protein in metastatic colorectal carcinomas. PMID: 10535485 Ref: [Mechanisms for resistance to anticancer agents and the reversal of the resistance]. PMID: 10695015 Ref: [Expression of multidrug resistance-associated protein (MRP) and lung resistance protein (LRP) in human rectal carcinomas and its clinical significance]. PMID: 11776833 |
Ref: Discovery and characterization of OC144-093, a novel inhibitor of P-glycoprotein-mediated multidrug resistance. PMID: 10850444 Ref: Differential expression of sphingolipids in MRP1 overexpressing HT29 cells. PMID: 10861470 Ref: Increased expression of an ATP-binding cassette superfamily transporter, multidrug resistance protein 2, in human colorectal carcinomas. PMID: 10873092 Ref: New highly lipophilic camptothecin BNP1350 is an effective drug in experimental human cancer. PMID: 11004678 Ref: Induction of MRP1 and gamma-glutamylcysteine synthetase gene expression by interleukin 1beta is mediated by nitric oxide-related signalings in human colorectal cancer cells. PMID: 11025451 Ref: The human multidrug resistance-associated protein (MRP) gene family: from biological function to drug molecular design. PMID: 11097346 Ref: Alkali-catalyzed beta-elimination of periodate-oxidized glycans: a novel method of chemical deglycosylation of mucin gene products in paraffin embedded sections. PMID: 11425189 |
Ref: Reversal of LRP-associated drug resistance in colon carcinoma SW-620 cells. PMID: 11149411 Ref: Differential sensitivities of the MRP gene family and gamma-glutamylcysteine synthetase to prooxidants in human colorectal carcinoma cell lines with different p53 status. PMID: 11239498 Ref: Hyperthermia-induced nuclear translocation of transcription factor YB-1 leads to enhanced expression of multidrug resistance-related ABC transporters. PMID: 11369762 Ref: Reversal of cisplatin and multidrug resistance by ribozyme-mediated glutathione suppression. PMID: 11500053 Ref: Long-term cultivation of colorectal carcinoma cells with anti-cancer drugs induces drug resistance and telomere elongation: an in vitro study. PMID: 11518543 Ref: Characterization of a human colorectal carcinoma cell line with acquired resistance to flavopiridol. PMID: 11641415 |
Ref: Induction of multidrug resistance proteins MRP1 and MRP3 and gamma-glutamylcysteine synthetase gene expression by nonsteroidal anti-inflammatory drugs in human colon cancer cells. PMID: 11820781 Ref: Intestinal transport of irinotecan in Caco-2 cells and MDCK II cells overexpressing efflux transporters Pgp, cMOAT, and MRP1. PMID: 12065434 |
Ref: Gene expression of CYP3A4, ABC-transporters (MDR1 and MRP1-MRP5) and hPXR in three different human colon carcinoma cell lines. PMID: 12625868 Ref: Gene expression profiles of ABC transporters and cytochrome P450 3A in Caco-2 and human colorectal cancer cell lines. PMID: 12636175 |
Ref: Glucuronidation as a mechanism of intrinsic drug resistance in colon cancer cells: contribution of drug transport proteins. PMID: 14667926 Ref: MRP1 and glucosylceramide are coordinately over expressed and enriched in rafts during multidrug resistance acquisition in colon cancer cells. PMID: 15122583 Ref: Cyclooxygenase-2 gene induction causes CDDP resistance in colon cancer cell line, HCT-15. PMID: 15517878 |
Ref: Efflux of depsipeptide FK228 (FR901228, NSC-630176) is mediated by P-glycoprotein and multidrug resistance-associated protein 1. PMID: 15634944 |
Ref: Clinical pharmacokinetics of irinotecan-based chemotherapy in colorectal cancer patients. PMID: 18666754 |
Ref: Correlation of induction of ATP binding cassette transporter A5 (ABCA5) and ABCB1 mRNAs with differentiation state of human colon tumor. PMID: 17541169 Ref: Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer. PMID: 17615082 Ref: Functional evaluation of multidrug resistance transporter activity in surgical samples of solid tumors. PMID: 17767422 Ref: A novel method to quantify sphingosine 1-phosphate by immobilized metal affinity chromatography (IMAC). PMID: 17991617 |
Ref: Effect of pO2 on antitumor drug cytotoxicity on MDR and non-MDR variants selected from the LoVo metastatic colon carcinoma cell line. PMID: 18383825 Ref: Fractionated irradiation can induce functionally relevant multidrug resistance gene and protein expression in human tumor cell lines. PMID: 18582150 Ref: Folate deprivation induces BCRP (ABCG2) expression and mitoxantrone resistance in Caco-2 cells. PMID: 18623116 Ref: Celecoxib upregulates multidrug resistance proteins in colon cancer: lack of synergy with standard chemotherapy. PMID: 18690847 |
Ref: Cellular folate status modulates the expression of BCRP and MRP multidrug transporters in cancer cell lines from different origins. PMID: 19240161 Ref: Identification of a novel topoisomerase inhibitor effective in cells overexpressing drug efflux transporters. PMID: 19798419 Ref: Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells. PMID: 20024169 Ref: Expression of HSP27, HSP72 and MRP proteins in in vitro co-culture of colon tumour cell spheroids with normal cells after incubation with rhTGF- beta1 and/or CPT-11. PMID: 20093746 |
Ref: Molecular determinants of folate levels after leucovorin administration in colorectal cancer. PMID: 19636555 Ref: Effects of dietary ingredients on function and expression of P-glycoprotein in human intestinal epithelial cells. PMID: 20118549 Ref: Hepatocyte growth factor (HGF), heat shock proteins (HSPs) and multidrug resistance protein (MRP) expression in co-culture of colon tumor spheroids with normal cells after incubation with interleukin-1beta (IL-1beta) and/or camptothecin (CPT-11). PMID: 20726333 Ref: [Effects of changwelqing on nuclear translocation of Y-box binding protein-1 and expression of P-glycoprotein in human colon cancer cell line with drug-resistance induced by vincristine]. PMID: 20929136 Ref: [Effect and mechanism of DNMT inhibitor on the reversal of multidrug resistance in human colon cancer cell line sw620/L-OHP]. PMID: 21265097 |
Ref: Novel acrylonitrile derivatives, YHO-13177 and YHO-13351, reverse BCRP/ABCG2-mediated drug resistance in vitro and in vivo. PMID: 21566063 Ref: Modulation of doxorubicin resistance by the glucose-6-phosphate dehydrogenase activity. PMID: 21679161 Ref: Multidrug-resistance proteins are weak tumor associated antigens for colorectal carcinoma. PMID: 21740599 Ref: The role of paclitaxel in the development and treatment of multidrug resistant cancer cell lines. PMID: 21775090 Ref: [The effect of small GTPase Cdc42 on the multidrug resistance of oxaliplatin-resistant colon cancer cell lines]. PMID: 21866627 Ref: MC70 potentiates doxorubicin efficacy in colon and breast cancer in vitro treatment. PMID: 21925160 Ref: A combined experimental and mathematical approach for molecular-based optimization of irinotecan circadian delivery. PMID: 21931543 Ref: Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer. PMID: 22045187 |
Ref: The role of ABC transporters in progression and clinical outcome of colorectal cancer. PMID: 22294766 Ref: Diallyl sulfide, diallyl disulfide and diallyl trisulfide affect drug resistant gene expression in colo 205 human colon cancer cells in vitro and in vivo. PMID: 22397993 Ref: Can immunohistochemistry of multidrug-resistant proteins replace the histoculture drug response assay in colorectal adenocarcinomas? PMID: 22580657 Ref: Increased JNK1 signaling pathway is responsible for ABCG2-mediated multidrug resistance in human colon cancer. PMID: 22870247 |
Ref: A prospective validation pharmacogenomic study in the adjuvant setting of colorectal cancer patients treated with the 5-fluorouracil/leucovorin/oxaliplatin (FOLFOX4) regimen. PMID: 22868256 Ref: Role of conventional chemosensitivity test and tissue biomarker expression in predicting response to treatment of peritoneal carcinomatosis from colon cancer. PMID: 23332421 Ref: Omega 3 fatty acids chemosensitize multidrug resistant colon cancer cells by down-regulating cholesterol synthesis and altering detergent resistant membranes composition. PMID: 24225025 Ref: Galectin-3 silencing inhibits epirubicin-induced ATP binding cassette transporters and activates the mitochondrial apoptosis pathway via beta-catenin/GSK-3beta modulation in colorectal carcinoma. PMID: 24303084 Ref: Synchronous rectal and gastric cancer in a fighter pilot: aeromedical concerns. PMID: 24426647 |
Ref: Correlation of Nrf2, NQO1, MRP1, cmyc and p53 in colorectal cancer and their relationships to clinicopathologic features and survival. PMID: 24695690 Ref: Selective cellular uptake and retention of SN 28049, a new DNA-binding topoisomerase II-directed antitumor agent. PMID: 24801172 Ref: Liposomal nitrooxy-doxorubicin: one step over caelyx in drug-resistant human cancer cells. PMID: 25057799 Ref: Genetic markers for toxicity of adjuvant oxaliplatin and fluoropyrimidines in the phase III TOSCA trial in high-risk colon cancer patients. PMID: 25370899 Ref: [Function of death associated protein kinase(DAPK) in colorectal cancer chemoresistance]. PMID: 25421769 |
Ref: Knockdown of Akt2 expression by shRNA inhibits proliferation, enhances apoptosis, and increases chemosensitivity to paclitaxel in human colorectal cancer cells. PMID: 25134663 Ref: Decreased functional activity of multidrug resistance protein in primary colorectal cancer. PMID: 25885226 Ref: Hypoxia-inducible factor-1alpha induces multidrug resistance protein in colon cancer. PMID: 26251616 |
Ref: Histone deacetylase 2 regulates doxorubicin (Dox) sensitivity of colorectal cancer cells by targeting ABCB1 transcription. PMID: 26846508 Ref: The hypoxia-mimetic agent CoCl(2) induces chemotherapy resistance in LOVO colorectal cancer cells. PMID: 26846577 Ref: miR-139-5p sensitizes colorectal cancer cells to 5-fluorouracil by targeting NOTCH-1. PMID: 27173050 Ref: Drug membrane transporters and CYP3A4 are affected by hypericin, hyperforin or aristoforin in colon adenocarcinoma cells. PMID: 27261575 Ref: Butyrate-mediated acquisition of chemoresistance by human colon cancer cells. PMID: 27277338 Ref: SYNTHESIS AND CYTOTOXIC ACTIVITY OF NEW 5H-INDOLO[2,3-B]QUINOLINE O-AMINOGLYCOSIDES. PMID: 27476287 Ref: Decellularized matrices as in vitro models of extracellular matrix in tumor tissues at different malignant levels: Mechanism of 5-fluorouracil resistance in colorectal tumor cells. PMID: 27558478 Ref: Synergistic anticancer effect of exogenous wild-type p53 gene combined with 5-FU in human colon cancer resistant to 5-FU in vivo. PMID: 27621580 Ref: Wnt-beta-catenin signaling regulates ABCC3 (MRP3) transporter expression in colorectal cancer. PMID: 27709738 Ref: Molecular features of doxorubicin-resistance development in colorectal cancer CX-1 cell line. PMID: 27746118 |
Ref: 2-Deoxy-D-glucose suppresses the migration and reverses the drug resistance of colon cancer cells through ADAM expression regulation. PMID: 28059830 Ref: The role of MRP1 in the multidrug resistance of colorectal cancer. PMID: 28454422 Ref: [MiR-145 inhibits drug resistance to Oxaliplatin in colorectal cancer cells through regulating G protein coupled receptor 98]. PMID: 28534337 Ref: Aldose reductase inhibitor increases doxorubicin-sensitivity of colon cancer cells and decreases cardiotoxicity. PMID: 28600556 Ref: Twist1 confers multidrug resistance in colon cancer through upregulation of ATP-binding cassette transporters. PMID: 28881781 Ref: miR-133b down-regulates ABCC1 and enhances the sensitivity of CRC to anti-tumor drugs. PMID: 28881788 Ref: HES1 Promotes Colorectal Cancer Cell Resistance To 5-Fu by Inducing Of EMT and ABC Transporter Proteins. PMID: 28928869 Ref: Modulation of the mRNA-binding protein HuR as a novel reversal mechanism of epirubicin-triggered multidrug resistance in colorectal cancer cells. PMID: 28968471 |
Ref: The reversal effect of Ginsenoside Rh2 on drug resistance in human colorectal carcinoma cells and its mechanism. PMID: 29582366 Ref: Effects of increased accumulation of doxorubicin due to emodin on efflux transporter and LRP1 expression in lung adenocarcinoma and colorectal carcinoma cells. PMID: 29644529 Ref: IL-8 regulates the doxorubicin resistance of colorectal cancer cells via modulation of multidrug resistance 1 (MDR1). PMID: 29693201 Ref: KDM5c inhibits multidrug resistance of colon cancer cell line by down-regulating ABCC1. PMID: 30257334 Ref: ANRIL promotes chemoresistance via disturbing expression of ABCC1 by regulating the expression of Let-7a in colorectal cancer. PMID: 30279206 |