Primary Site >> Biliary tract Cancer
Gene >> ABCB4
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Ref: beta-Adrenoceptor blockade in sclerosing cholangitis of Mdr2 knockout mice: antifibrotic effects in a model of nonsinusoidal fibrosis. PMID: 20921947 Ref: Genetic factors in the pathogenesis of cholangiocarcinoma. PMID: 21691113 |
Ref: Aspects of liver pathology in adult patients with MDR3/ABCB4 gene mutations. PMID: 22331132 |
Ref: Telmisartan plus propranolol improves liver fibrosis and bile duct proliferation in the PSC-like Abcb4-/- mouse model. PMID: 23247798 Ref: Hepatobiliary anomalies associated with ABCB4/MDR3 deficiency in adults: a pictorial essay. PMID: 23591976 |
Ref: Molecular mechanisms for biliary phospholipid and drug efflux mediated by ABCB4 and bile salts. PMID: 25133187 |
Ref: Epithelial Transforming Growth Factor-beta Signaling Does Not Contribute to Liver Fibrosis but Protects Mice From Cholangiocarcinoma. PMID: 26627606 Ref: BSEP and MDR3: Useful Immunohistochemical Markers to Discriminate Hepatocellular Carcinomas From Intrahepatic Cholangiocarcinomas and Hepatoid Carcinomas. PMID: 26735860 |
Ref: Substance P increases liver fibrosis by differential changes in senescence of cholangiocytes and hepatic stellate cells. PMID: 28256736 Ref: Common genetic variation and risk of gallbladder cancer in India: a case-control genome-wide association study. PMID: 28274756 |
Ref: Blocking H1/H2 histamine receptors inhibits damage/fibrosis in Mdr2(-/-) mice and human cholangiocarcinoma tumorigenesis. PMID: 29601088 |