Primary Site >> Biliary tract Cancer

Gene >> ABCB1

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Ref: [Analysis of MDR1 (multidrug resistance) gene expression by RT-PCR].
PMID: 8387754
 Ref: Clinical relationship between MDR1 gene and gallbladder cancer.
PMID: 15138130
 Ref: Drug sensitivity and drug resistance profiles of human intrahepatic cholangiocarcinoma cell lines.
PMID: 15884115
 Ref: [Somatostatin enhanced anti-tumor effect of doxorubicin on gallbladder cancer cells through the regulation of intracellular drug concentration].
PMID: 21162905
 Ref: Prognostic value of ABCG2 in moderately and poorly differentiated intrahepatic cholangiocarcinoma.
PMID: 21884202
 Ref: Cytotoxicity, toxicity, and anticancer activity of Zingiber officinale Roscoe against cholangiocarcinoma.
PMID: 23167387
Ref: High expression of ABCC1 indicates poor prognosis in intrahepatic cholangiocarcinoma.
PMID: 23480753
 Ref: Mechanisms of verapamil-enhanced chemosensitivity of gallbladder cancer cells to platinum drugs: glutathione reduction and MRP1 downregulation.
PMID: 23229154
 Ref: Notch1 is overexpressed in human intrahepatic cholangiocarcinoma and is associated with its proliferation, invasiveness and sensitivity to 5-fluorouracil in vitro.
PMID: 24700253
Ref: Molecular mechanisms for biliary phospholipid and drug efflux mediated by ABCB4 and bile salts.
PMID: 25133187
 Ref: A case of metastatic renal cell carcinoma and bile duct carcinoma treated with a combination of sunitinib and gemcitabine.
PMID: 26001650
Ref: NOX1 mediates chemoresistance via HIF1alpha/MDR1 pathway in gallbladder cancer.
PMID: 26545779
 Ref: Inhibition of mTOR suppresses human gallbladder carcinoma cell proliferation and enhances the cytotoxicity of 5-fluorouracil by downregulating MDR1 expression.
PMID: 27212159
 Ref: Common genetic variation and risk of gallbladder cancer in India: a case-control genome-wide association study.
PMID: 28274756
Ref: miR-218-5p restores sensitivity to gemcitabine through PRKCE/MDR1 axis in gallbladder cancer.
PMID: 28492560