Primary Site >> Colorectal Cancer

Gene >> AADAC

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Ref: p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage.
PMID: 18223691
Ref: DSC3 expression is regulated by p53, and methylation of DSC3 DNA is a prognostic marker in human colorectal cancer.
PMID: 21364582
Ref: Different involvement of DNA methylation and histone deacetylation in the expression of solute-carrier transporters in 4 colon cancer cell lines.
PMID: 22382314
Ref: Epigenetic silencing of CXCL14 induced colorectal cancer migration and invasion.
PMID: 24099668
Ref: Different effects of epigenetic modifiers on the cytotoxicity induced by 5-fluorouracil, irinotecan or oxaliplatin in colon cancer cells.
PMID: 24172061
Ref: Regulation and expression of aberrant methylation on irinotecan metabolic genes CES2, UGT1A1 and GUSB in the in-vitro cultured colorectal cancer cells.
PMID: 24439671
Ref: Calcium-sensing receptor silencing in colorectal cancer is associated with promoter hypermethylation and loss of acetylation on histone 3.
PMID: 24691920
Ref: Epigenetic inactivation of the novel candidate tumor suppressor gene ITIH5 in colon cancer predicts unfavorable overall survival in the CpG island methylator phenotype.
PMID: 25093535
Ref: Effects of Decitabine on Invasion and Exosomal Expression of miR-200c and miR-141 in Oxaliplatin-Resistant Colorectal Cancer Cells.
PMID: 26179333
Ref: Systematic discovery of drug action mechanisms by an integrated chemical genomics approach: identification of functional disparities between azacytidine and decitabine.
PMID: 27036028