literature

SARS_CoV_2 mutation literature information.

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a Dog in Connecticut in February 2021.

PMID: 34834948 2021 Viruses

Result: We found amino acid substitutions in Spike (D614G), N (D377Y, P67S, P199L), NS3 (G172V, Q57H), NS8 (S24L) NSP2 (T85I), NSP4 (M458I), NSP5 (L89F), NSP12 (P323L), NSP14 (N129D), and NSP16 (R216C) proteins.

SARS-CoV-2 genetic variations associated with COVID-19 pathogenicity.

PMID: 34870573 2021 Microbial genomics

Table: T85I

Analysis of 329,942 SARS-CoV-2 records retrieved from GISAID database.

PMID: 34735950 2021 Computers in biology and medicine

Discussion: T85I is noted to co-occur with Q57H, and P504L - with Y541C.

The Algerian Chapter of SARS-CoV-2 Pandemic: An Evolutionary, Genetic, and Epidemiological Prospect.

PMID: 34452390 2021 Viruses

Discussion: This included T85I in the nsp2 gene, P423L in the nsp12 gene, D614G in the S gene, and Q57H in the ORF3a gene.

Emergence and expansion of SARS-CoV-2 B.1.526 after identification in New York.

PMID: 34428777 2021 Nature

Introduction: Non-spike mutations widely shared by B.1.526-E484K and B.1.526-S477N isolates include: T85I in ORF1a-nsp2; L438P in ORF1a-nsp4, a 9-base pair (bp) deletion (Delta106-108) in ORF1a-nsp6; P323L in ORF1b-nsp12; Q88H in ORF1b-nsp13; Q57H in ORF3a; and P199L and M234I in the N<

Correlates of SARS-CoV-2 Variants on Deaths, Case Incidence and Case Fatality Ratio among the Continents for the Period of 1 December 2020 to 15 March 2021.

PMID: 34356077 2021 Genes

Result: The NSP2_T85I mutation was reported at 40.20% and 59.59% in SARS-CoV-2 genome sequences isolated from Africa and South America, respectively.

Evolutionary Tracking of SARS-CoV-2 Genetic Variants Highlights an Intricate Balance of Stabilizing and Destabilizing Mutations.

PMID: 34281387 2021 mBio

Abstract: In addition, a retention of Q57H (B.1.X), R203K/G204R (B.1.1.X), T85I (B.1.2-B.1.3), G15S+T428I (C.X), and I120F (D.X) variations was observed.

Result: Other major mutations noted are Q57H (26.5%), R203K/G204R (33%), G15S (12%), I120F (11.5%), and T85I (14%).

Result: These are Q57H (nucleotide 25,563, G to T) in ORF3a, the R203K + G204R combination (nucleotide 28,881, GGG to AAC)

High-precision and cost-efficient sequencing for real-time COVID-19 surveillance.

PMID: 34211026 2021 Scientific reports

Result: Eight other sequences had mutations of T85I in the NSP2 protein and Q57H in the ORF3a protein (red circle in.

Result: In USA and California, the prevalence of T85I in NSP2 and Q57H in ORF3a were observed to be above 40%, as shown in.

Table: T85I

Multilevel systems biology analysis of lung transcriptomics data identifies key miRNAs and potential miRNA target genes for SARS-CoV-2 infection.

PMID: 34157472 2021 Computers in biology and medicine

Table: T85I

Mutation Signatures and In Silico Docking of Novel SARS-CoV-2 Variants of Concern.

PMID: 33925854 2021 Microorganisms

Result: The COH-VOC has two mutations at positions N501Y and D614G in the S-protein, while harboring several mutations in the NSP2 (T85I), NSP3 (T181I, A256V), NSP5 (L89F, P108S), NSP6 (G258E), NSP12 (P323L), NSP14 (N129D), and NSP16 (R216C), NS3 (Q57H, G172V), NS7a (

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