literature

SARS_CoV_2 mutation literature information.

Antibody escape and global spread of SARS-CoV-2 lineage A.27.

PMID: 35241661 2022 Nature communications

Table: T28144C

Discussion: The root of the pandemic lies in the parental A lineage with the characteristic C8782T and T28144C mutations.

In-silico genomic landscape characterization and evolution of SARS-CoV-2 variants isolated in India shows significant drift with high frequency of mutations.

PMID: 35233173 2022 Saudi journal of biological sciences

Discussion: Our results disagreed with who studied the mutations among SARS-CoV-2 collected from various locations and reported C29095T in the N gene, T28144C in the ORF8 gene, and C8782T in the ORF1ab gene as the most frequent mutations.

Comparison of SARS-CoV-2 Evolution in Paediatric Primary Airway Epithelial Cell Cultures Compared with Vero-Derived Cell Lines.

PMID: 35215919 2022 Viruses

Result: Analysing mutations in the PHE passage series, we identified four changes (C8782T; T18488T; T28144C; A29596G) relative to Wuhan-Hu-1 consistently at ~100% at all passages, likely reflecting fixation in the original virus stock (Figure 2a).

Characterization of SARS-CoV-2 different variants and related morbidity and mortality: a systematic review.

PMID: 34103090 2021 European journal of medical research

Table: T28144C

Discussion: In other words, the S variant (Type A) with two mutations at 8782C>T and 28144 T>C was mainly identified in East Asia.

Genomic mutations and changes in protein secondary structure and solvent accessibility of SARS-CoV-2 (COVID-19 virus).

PMID: 33568759 2021 Scientific reports

Introduction: Among them, the mutations at position C8782T in the ORF1ab gene, T28144C in the ORF8 gene and C29095T in the N gene are common.

Genome-wide analysis of SARS-CoV-2 strains circulating in Vietnam: Understanding the nature of the epidemic and role of the D614G mutation.

PMID: 34042186 2021 Journal of medical virology

Result: ORF8 had one missense mutation at position T28144C that led to an amino acid change from Leucine to Serine (L84S).

SARS-CoV-2 mutations: the biological trackway towards viral fitness.

PMID: 33928885 2021 Epidemiology and infection

Introduction: Cluster I includes 3037C>T; NSP3:F106F (non-structural protein3:F106F) and 14408C>T; RdRp:P323L, cluster II includes 3037C>T, 14408C>T and 23403A>G; S:D614G, cluster III includes 14408C>T, cluster IV includes 3037C>T, 14408C>T, 23403A>G, 28881G>A; N:R203K, 28882G>A

Genomic Variations in SARS-CoV-2 Genomes From Gujarat: Underlying Role of Variants in Disease Epidemiology.

PMID: 33815459 2021 Frontiers in genetics

Table: T28144C

Pan-India novel coronavirus SARS-CoV-2 genomics and global diversity analysis in spike protein.

PMID: 33758785 2021 Heliyon

Result: Clades are characterized as S (C8782T, T28144C, NS8-L84S), L (C241, C3037, A23403, C8782, G11083, G25563, G26144, T28144, G228882), V (NSP6-L37F, NS3-G251V), G (S-D614S), GH (S-D614S, NS3-Q57H), S (S-D614S, NG204R).

Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants.

PMID: 33589648 2021 Communications biology

Result: In Cluster A, B, C, and D, the co-mutations with the highest number of descendants are [241C>T, 3037C>T, 14408C>T, 23403A>G], [3037C>T, 14408C>T], [8782C>T, 18060C>T, 28144T>C], and [3037C>T, 14408C>T, 23403A>G] respectively.

Result: In contrast, the time evolution plot shows that the ratio of mutatio

Result: Mutation 28144T>C-(L84S), the first known mutation globally, has had a very unsteady trajectory.

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