literature

SARS_CoV_2 mutation literature information.

Relative Consolidation of the Kappa Variant Pre-Dates the Massive Second Wave of COVID-19 in India.

PMID: 34828410 2021 Genes

Discussion: Among the non-spike proteins, the kappa variant harbors the R203M mutation at the edge of the Serine/Arginine (SR) rich domain of N protein and shares sequence variations in this mutational hotspot with the alpha (R203M) and beta (T205I) variants.

An outbreak of SARS-CoV-2 with high mortality in mink (Neovison vison) on multiple Utah farms.

PMID: 34767598 2021 PLoS pathogens

Result: One of the two mink from farm A had mutations at T85I-NSP2, S1205L-NSP3, G37E-NSP9, P323L-NSP12, T91M-NSP15, D614G-spike, N501T-spike, Q57H-NS3, H182Y-NS3, and T205I-N as compared to hCoV-19/Wuhan/WIV04/2019.

Table: T205I

Insights on the SARS-CoV-2 genome variability: the lesson learned in Brazil and its impacts on the future of pandemics.

PMID: 34730486 2021 Microbial genomics

Discussion: Moreover, the variants of concern B.1.351, B.1.427, and B.1.429 feature the T205I substitution, which were identified in 0.69% of our sequences from May to September (Table S1).

Genomic surveillance reveals the detection of SARS-CoV-2 delta, beta, and gamma VOCs during the third wave in Pakistan.

PMID: 34726786 2021 Journal of medical virology

Result: The mutational analysis revealed that all the beta variant isolates reported significant and lineage defining mutations as: ORF1a:K1655N (NSP3: K837N) (5230 G>T), S:D80A (21801 A>C), S:D215G (22206 A>G), S:K417N (22813 G>T), S:E484K (23012 G>A), S:N501Y (23063 A>T),

Temporal-Geographical Dispersion of SARS-CoV-2 Spike Glycoprotein Variant Lineages and Their Functional Prediction Using in Silico Approach.

PMID: 34700382 2021 mBio

Result: Other than the S protein, the majority of beta (B.1.351) genomes had amino acid changes within ORF1a (T265I, K1655N, K3353R), ORF1b (P214L), ORF3a (Q57H, S171L), E (P71L), and N (T205I).

Evolution, Mode of Transmission, and Mutational Landscape of Newly Emerging SARS-CoV-2 Variants.

PMID: 34465019 2021 mBio

Table: T205I

Diagnostic pre-screening method based on N-gene dropout or delay to increase feasibility of SARS-CoV-2 VOC B.1.1.7 detection.

PMID: 34464903 2021 Diagnostic microbiology and infectious disease

Discussion: In other variants of concern, such as the B 1.351 and P.1 variants, the main mutations in the N protein are non-synonymous ones, such as T205I and P80R, respectively.

Coding-Complete Genome Sequences of 11 SARS-CoV-2 B.1.1.7 and B.1.351 Variants from Metro Manila, Philippines.

PMID: 34264104 2021 Microbiology resource announcements

Table: T205I

Novel Highly Divergent SARS-CoV-2 Lineage With the Spike Substitutions L249S and E484K.

PMID: 34262921 2021 Frontiers in medicine

Table: T205I

Genomic monitoring unveil the early detection of the SARS-CoV-2 B.1.351 (beta) variant (20H/501Y.V2) in Brazil.

PMID: 34241897 2021 Journal of medical virology

Result: The B.1.351 VOC was characterized by K417N, E484K, N501Y in the spike region and 19 mutations and 2 deletions as follows: ORF1ab: T265I, R724K, S1612L, K1655N, K3353R, SGF 3675_F3677del, P4715L, E5585D; spike: D80A, D215G, L242_L244del, A262D, D614G, C1247F; ORF3a: Q57H,

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