Phylodynamic Pattern of Genetic Clusters, Paradigm Shift on Spatio-Temporal Distribution of Clades, and Impact of Spike Glycoprotein Mutations of SARS-CoV-2 Isolates from India.
PMID: 35017872
2021
Journal of global infectious diseases
Discussion: Besides, D614G in combination with other mutations such as D614G+L5F (n = 23), D614G+V341I (n = 1), D614G+D936Y (n = 3), D614G+S939F (n = 9) and D614G+S943T (n = 2) in strains of the present study was demonstrated to have increased infectivity compared to Wuhan-1 strain.
The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity.
Result: Notably, single D614G and combined variants with D614G (D614G+L5F, D614G+V341I, D614G+K458R, D614G+I472V, D614G+D936Y, D614G+S939F, and D614G+S943T) demonstrated increased infectivity compared to the reference strain in all the four cell lines (Figures 3A-3D), whereas no difference was found between single D614G and D614G combined variants, suggesting that the en
SARS-CoV-2 genomic and quasispecies analyses in cancer patients reveal relaxed intrahost virus evolution.
Result: Another 85 SNVs were observed in our sequences in a lower frequency (1.4-19.7%; S2 Table), including nine non-synonymous mutations in S protein (V16F, V367L, K558N, Q675H, A879V, S939F, V1176F, K1191N and G1219V).
SARS_CoV_2 mutation literature information.
PMID: 
2021
mBio
Browser Board
Co-occurred Entities
Filtrator
ViMRT