Result: Among the nine variations, six (C6312T, C8637T, A10124G, C17518T, C23664T, and C28854T) caused amino acid substitutions (nsp3-T1198I, nsp4-T28I, nsp5-T24A, nsp13-L428F, S-A701V, and N-S194L).
Table: S194L
Infection, recovery and re-infection of farmed mink with SARS-CoV-2.
Genome-wide identification and prediction of SARS-CoV-2 mutations show an abundance of variants: Integrated study of bioinformatics and deep neural learning.
PMID: 34812411
2021
Informatics in medicine unlocked
4Method: In I2, R203K/G204R present an r- with LG_4, an r- with S194L, an r+ with LG_5 and an r+ with S477N (""Cor_mut.pdf"" in Data S1)."
Method: We first created 7-bp sequences by combining the nucleotide sequences of different strains at seven mutation sites (R203K/G204R (LG_3), N501Y (LG_5), A222V (LG_4), C313T, S477N, S194L and I120F).
Phylogenomics and population genomics of SARS-CoV-2 in Mexico during the pre-vaccination stage reveals variants of interest B.1.1.28.4 and B.1.1.222 or B.1.1.519 and the nucleocapsid mutation S194L associated with symptoms.
Abstract: We identified the mutation N:S194L of the nucleocapsid protein associated with symptomatic patients.
Introduction: Based on this, we identified mutation N:S194L of the nucleocapsid to be potentially associated with the development of symptoms.
Result: However, many different Pangolin lineages are annotated within the implicated N:S194L-containing 20A sub-clade of scenario (i).
Result: In addition to the B.1 lineage within these two 20A sub-clades, lineage B.1.243, with 78 genome sequences sharing the point mutation N:S194L and the deletion NS9c:Q41* (22.8 % of total sequences within these two 20A clades and 5.1 % of the
Spatial epidemiology and genetic diversity of SARS-CoV-2 and related coronaviruses in domestic and wild animals.
Abstract: The results showed that four types of mutations caused dramatic changes in protein structures (RMSD >= 5.0 A), which were Q57H and G251V in open-reading frames 3a (ORF3a), S194L, and R203K/G204R in nucleocapsid (N).
Result: 11 After structural alignment, we found that four mutants exhibited a significant difference in protein structural morphology from their control ones (RMSD >= 5.0 A), which were Q57H Orf3a, G251V Orf3a, S194L N, a
Comparative insight into the genomic landscape of SARS-CoV-2 and identification of mutations associated with the origin of infection and diversity.
SARS_CoV_2 mutation literature information.
PMID: 
2021
Scientific reports
Browser Board
Co-occurred Entities
Filtrator
ViMRT