literature

SARS_CoV_2 mutation literature information.

Evolutionary analysis of the Delta and Delta Plus variants of the SARS-CoV-2 viruses.

PMID: 34399188 2021 Journal of autoimmunity

Abstract: Furthermore, five key mutations (T95I, A222V, G142D, R158G, and K417N) were significantly more prevalent in the Delta Plus than in the Delta variant.

Introduction: To assess how Delta Plus was evolving from Delta, we determined the prevalence of six key mutations (T95I,

Introduction: To assess if mutations change sidechain conformation, we generated mutations W258A, G142D and R158G using Prime software of Schrodinger Suite (Schrodinger LLC, NY).

SARS-CoV-2 B.1.1.7 sensitivity to mRNA vaccine-elicited, convalescent and monoclonal antibodies.

PMID: 33619509 2021 medRxiv

Table: R158G

Community-level SARS-CoV-2 sequence diversity revealed by wastewater sampling.

PMID: 34438144 2021 The Science of the total environment

Table: R158G

Evolution, Mode of Transmission, and Mutational Landscape of Newly Emerging SARS-CoV-2 Variants.

PMID: 34465019 2021 mBio

Table: R158G

The in vitro and in vivo efficacy of CT-P59 against Gamma, Delta and its associated variants of SARS-CoV-2.

PMID: 34547629 2021 Biochemical and biophysical research communications

Table: R158G

Evaluation of the clinical and analytical performance of the Seegene allplex SARS-CoV-2 variants I assay for the detection of variants of concern (VOC) and variants of interests (VOI).

PMID: 34628158 2021 Journal of clinical virology

Table: R158G

SARS-CoV-2 Virus-Host Interaction: Currently Available Structures and Implications of Variant Emergence on Infectivity and Immune Response.

PMID: 34639178 2021 International journal of molecular sciences

Discussion: In the Delta variant, mutations T19R, E156-, F157- and R158G severely affect NTD directed Abs, due to the adoption of an alpha-helical conformation, instead of the original beta-strand.

Spike protein evolution in the SARS-CoV-2 Delta variant of concern: a case series from Northern Lombardy.

PMID: 34651569 2021 Emerging microbes & infections

Abstract: More patients tested positive for G769 V plus C1248F, A352S, and R158G and C1248F, respectively.

Result: The sequence confirmed Delta variant additionally harbouring R158G and C1248F.

Table: R158G

Prior infection with SARS-CoV-2 boosts and broadens Ad26.COV2.S immunogenicity in a variant-dependent manner.

PMID: 34688376 2021 Cell host & microbe

Method: SARS-CoV-2 pseudotyped lentiviruses were prepared by co-transfecting the HEK293T cell line with either the SARS-CoV-2 ancestral variant spike (D614G), the Beta spike (L18F, D80A, D215G, K417N, E484K, N501Y, D614G, A701V, 242-244 del) or the Delta spike (T19R, R158G L452R, T478K, D614G, P681R, D950N, 156-157 del) plasmids in co

SARS-CoV-2 Delta (B.1.617.2) Variant: A Unique T478K Mutation in Receptor Binding Motif (RBM) of Spike Gene.

PMID: 34796036 2021 Immune network

Abstract: Recently, SARS-CoV-2 delta variant prevails over different countries that have 3 unique mutation sites: E156del/R158G in the N-terminal domain and T478K in a crucial receptor binding domain.

Introduction: The comparison of SARS-CoV-2 delta variant with other variants revealed 3 unique mutation sites, E156del, R158G, and T478K, which were indicated by red letter (Table 1 and.

Method: The three unique mutation sites, E156del, R158G, and T478K in the SARS-CoV-2 delta variant must be investigated if a recent outbreak of COVID-19

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