literature

SARS_CoV_2 mutation literature information.

Serum Neutralizing Activity of mRNA-1273 against SARS-CoV-2 Variants.

PMID: 34549975 2021 Journal of virology

Table: Q613H

Phylogenomics and population genomics of SARS-CoV-2 in Mexico during the pre-vaccination stage reveals variants of interest B.1.1.28.4 and B.1.1.222 or B.1.1.519 and the nucleocapsid mutation S194L associated with symptoms.

PMID: 34846283 2021 Microbial genomics

Discussion: A case exemplifying a similar scenario in which physically close mutations contribute towards an analogous structural solution is provided by the spike protein mutation Q613H.

Discussion: In this case, mutation Q613H defining the emerging lineage A.23.1, from Uganda, may have taken the role of the mutation D614G in B lineages during evolution of A lineages.

Additional Positive Electric Residues in the Crucial Spike Glycoprotein S Regions of the New SARS-CoV-2 Variants.

PMID: 34880635 2021 Infection and drug resistance

Table: Q613H

Spatial epidemiology and genetic diversity of SARS-CoV-2 and related coronaviruses in domestic and wild animals.

PMID: 34910734 2021 PloS one

Result: Some mutations in S protein like L54F, P681L, L18F, S494P, Q613H, L560P, T299A, V1104L, L1063F, Q675R, D138Y, A522S, A845S were only detected in cat, not in any other animal species.

A Genomic Snapshot of the SARS-CoV-2 Pandemic in the Balearic Islands.

PMID: 35095814 2021 Frontiers in microbiology

Abstract: Additional spike mutations were rarely documented with the exception of mutation S:Q613H which has been detected in several genomes (n = 25) since July 2021.

Result: Of note, since July 2021, mutation S:Q613H present in lineage A.23.1 has been detected in a relative high number of genomes belonging to the P.1 (n = 1) and B.1.617.2/AY.X (n = 24) lineages, mutation which could provide some biological advantages.

Discussion: Nevertheless, in late weeks, the additional spike substitution S:Q613H has been detected in an increasing number of genomes belonging to the Delta variant.

Design of a companion bioinformatic tool to detect the emergence and geographical distribution of SARS-CoV-2 Spike protein genetic variants.

PMID: 33380328 2020 Journal of translational medicine

Result: Next, there are a few variants with a frequency of 2-7% that are slowly rising in the viral populations, namely S477N, Q613H and A222V.

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