literature

SARS_CoV_2 mutation literature information.

Correlates of SARS-CoV-2 Variants on Deaths, Case Incidence and Case Fatality Ratio among the Continents for the Period of 1 December 2020 to 15 March 2021.

PMID: 34356077 2021 Genes

Result: The NS3_Q57H mutation was reported at 46.10%, 32.99% and 63.30% in SARS-CoV-2 genome sequences isolated from Africa, Australia and North America, respectively.

Near-Complete Genome Sequences of Nine SARS-CoV-2 Strains Harboring the D614G Mutation in Malaysia.

PMID: 34351228 2021 Microbiology resource announcements

Table: Q57H

Ongoing global and regional adaptive evolution of SARS-CoV-2.

PMID: 34292871 2021 Proc Natl Acad Sci U S A

Result: Q57H is the fourth most common positively selected mutation.

Result: In addition to the many mutations of interest in the N and S proteins, Orf3a Q57H is a signature mutation for partitions 6, 7, and v1.

Multilevel systems biology analysis of lung transcriptomics data identifies key miRNAs and potential miRNA target genes for SARS-CoV-2 infection.

PMID: 34157472 2021 Computers in biology and medicine

Table: Q57H

An Epidemiological Analysis of SARS-CoV-2 Genomic Sequences from Different Regions of India.

PMID: 34067745 2021 Viruses

Result: Firstly, the GR-GH variants defined by the presence of the D614G, G204R, and Q57H mutations in the S, N, and ORF3a proteins, respectively, were observed in 14 sequences from different parts of India, starting from May 2020 (Figure 2).

High Prevalence of SARS-CoV-2 Genetic Variation and D614G Mutation in Pediatric Patients With COVID-19.

PMID: 34095334 2021 Open forum infectious diseases

Discussion: G25563T leads to the Q57H missense mutation ORF3a that is associated with host cell apoptosis and contributes to increased infectivity and virulence.

Characterization of SARS-CoV-2 different variants and related morbidity and mortality: a systematic review.

PMID: 34103090 2021 European journal of medical research

Table: Q57H

Global variation in SARS-CoV-2 proteome and its implication in pre-lockdown emergence and dissemination of 5 dominant SARS-CoV-2 clades.

PMID: 34147651 2021 Infection, genetics and evolution

Figure: B-H) Global distribution of (represented by percentage frequency) highly recurring mutations: B) Nsp2:T85I, C) Nsp6:L37F, D) Nsp12:P323L, E) Spike:D614G, F) ORF3a:Q57H, G) N protein:R203K and H) N protein:G204R.

Discussion: For instance, Nsp2:T85I and ORF3a:Q57H (mostly occur together) along with Spike:

Development of a genotyping platform for SARS-CoV-2 variants using high-resolution melting analysis.

PMID: 34154921 2021 Journal of infection and chemotherapy

Table: Q57H

Genomic monitoring unveil the early detection of the SARS-CoV-2 B.1.351 (beta) variant (20H/501Y.V2) in Brazil.

PMID: 34241897 2021 Journal of medical virology

Result: The B.1.351 VOC was characterized by K417N, E484K, N501Y in the spike region and 19 mutations and 2 deletions as follows: ORF1ab: T265I, R724K, S1612L, K1655N, K3353R, SGF 3675_F3677del, P4715L, E5585D; spike: D80A, D215G, L242_L244del, A262D, D614G, C1247F; ORF3a: Q57H,

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