Abstract: Molecular docking analysis revealed that
G462D/G462S variants were predicted to be protective variants, whereas
Q438E and
S339F variants were predicted to increase susceptibility.
Discussion: In contrast, the
Q438E and
S339F variants improved binding affinities to the
S glycoprotein at cleavage sites one and two, respectively.
Discussion: Thus, the
Q438E and
S339F variants will likely render individuals harboring these polymorphisms more susceptible to
SARS-CoV-2 infection.
SARS_CoV_2 mutation literature information.
PMID: 
2022
Life (Basel, Switzerland)
Browser Board
Co-occurred Entities
Filtrator