Abstract: SARS-CoV-2 isolates from minks exhibited two amino acid substitutions (
G261D,
A262S) in the
N-terminal domain of
S protein and four (
L452M,
Y453F,
F486L,
N501T) in the receptor-binding motif (RBM).
Result: Fifteen unique mutations were identified in mink isolates (Table S2), four of which (
L452M,
Y453F,
F486L,
N501T) were located within the RBM of
S protein.
Discussion: In our study, all analyzed SARS-CoV-2 from animals had Q493 and N501 except mink isolates which had
N501T.
SARS_CoV_2 mutation literature information.
PMID: 
2020
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