literature

SARS_CoV_2 mutation literature information.

Omicron variant (B.1.1.529) of SARS-CoV-2: understanding mutations in the genome, S-glycoprotein, and antibody-binding regions.

PMID: 35258772 2022 GeroScience

Introduction: V445E and K444 Q/R/N in the RBD and K150 T/Q/R/E, and N148S in NTD may be responsible for antibody escape.

Comprehensive annotations of the mutational spectra of SARS-CoV-2 spike protein: a fast and accurate pipeline.

PMID: 32954666 2021 Transboundary and emerging diseases

Table: N148S

Mutational analysis in international isolates and drug repurposing against SARS-CoV-2 spike protein: molecular docking and simulation approach.

PMID: 34307771 2021 Virusdisease

Table: N148S

A Combination of Receptor-Binding Domain and N-Terminal Domain Neutralizing Antibodies Limits the Generation of SARS-CoV-2 Spike Neutralization-Escape Mutants.

PMID: 34607456 2021 mBio

Discussion: In addition, mutations at N148S, K150R/E, and S151P in the NTD epitope exhibited reductions in sensitivity to three COVID-19 convalescent-phase plasma samples.

Phylodynamic Pattern of Genetic Clusters, Paradigm Shift on Spatio-Temporal Distribution of Clades, and Impact of Spike Glycoprotein Mutations of SARS-CoV-2 Isolates from India.

PMID: 35017872 2021 Journal of global infectious diseases

Result: L18F, T19A, D80N, D138Y, Y144del, Y145del, K147E, N148S, W152 L, Q218H and S255F were found in NTD, and among them, L18F, Y144del, Y145del and N148S and W152 L were shown to display resistance to neutralizing antibodies.

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