Result: The T265I, D614G and L84S hotspot mutations located in orf1ab and Spike proteins respectively were introduced into the virus for the first time in late February (Fig 4B).
Result: The most represented was D614G mutation at spike protein with 43.46% (n = 1.333) of the genomes, the second was L84S (at ORF8) found in 23.21% (n = 712).
Result: The second subclade SCB2 also stared in China at the beginning of Jan and harbored the mutation L84S (ORF8).
Analysis of Indian SARS-CoV-2 Genomes Reveals Prevalence of D614G Mutation in Spike Protein Predicting an Increase in Interaction With TMPRSS2 and Virus Infectivity.
Result: Among the common variants, the most frequent mutations are 23403 A > G (D614G, S gene), 241 C > T (5' UTR), 14408 C > T (P4715L, RdRP gene), 3037 C > T (F942F, NSP3), 28881 G > A (R203K, N gene), 28882 G > A (R203R, N gene), 28883 G > C (G204R, N gene), and
Spike protein D614G and RdRp P323L: the SARS-CoV-2 mutations associated with severity of COVID-19.
SARS_CoV_2 mutation literature information.
PMID: 
2020
PloS one
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