Result: There were another three SNVs specific to males with a strong connection to the mortality, G11083T (nsp6:L37F), G28878A (ORF9:S202N), and G22468T (S:T302T), which all were enriched in the nondeath group.
Temporal landscape of mutational frequencies in SARS-CoV-2 genomes of Bangladesh: possible implications from the ongoing outbreak in Bangladesh.
Result: Moreover, several mutations were found that persisted, (I120F, T412I, L37F, P323L, G204R, R203K, and D614G) for more than 6 weeks (Table 1 and.
Evolutionary Tracking of SARS-CoV-2 Genetic Variants Highlights an Intricate Balance of Stabilizing and Destabilizing Mutations.
Result: The combination of G251V and L37F, which was initially considered a defining mutation pattern for the B.2 to B.6 lineage (clade V in GISAID classification), has shown under more detailed analysis that isolates carrying the G251V mutation are distributed in other lineages too.
Result: The subsequent amino acid substitutions L37F in ORF3a and G251V in nsp6 were found to be present in 13.3% and 1.4% of genomes, respectively.
Table: L37F
Biological Significance of the Genomic Variation and Structural Dynamics of SARS-CoV-2 B.1.617.
Result: All strains within this B.2/B.6 lineage shared genetic variation G11083T, encoded for amino acid changes from leucine to phenylalanine at position 37 of nsp6 in ORF1ab.
Table: L37F
Host Response to SARS-CoV2 and Emerging Variants in Pre-Existing Liver and Gastrointestinal Diseases.
PMID: 34760721
2021
Frontiers in cellular and infection microbiology
Introduction: Further, L clade evolved to V (G11083T, G26144T, NSP6-L37F + NS3-G251V) and G (C241T, C3037T, A23403G, and S-D614G); and later G clade evolved into GH (C241T, C3037T, A23403G, G25563T includes S-D614G + NS3-Q57H), GR (C241T, C3037T,
Molecular epidemiology of SARS-CoV-2 isolated from COVID-19 family clusters.
SARS_CoV_2 mutation literature information.
PMID: 
2021
Journal of infection and chemotherapy
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