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iMRT
SARS_CoV_2-M: K444Q
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SARS_CoV_2 mutation literature information.
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1
A Detailed Overview of Immune Escape, Antibody Escape, Partial Vaccine Escape of SARS-CoV-2 and Their Emerging Variants With Escape Mutations.
PMID:
35222380
2022
Frontiers in immunology
Introduction:
Three mutants were identified at 444 positions in the
RBD
region:
K444R
,
K444Q
, and
K444N
.
2
Omicron variant (B.1.1.529) of SARS-CoV-2: understanding mutations in the genome, S-glycoprotein, and antibody-binding regions.
PMID:
35258772
2022
GeroScience
Introduction:
V445E
and
K444 Q/R/N
in the
RBD
and
K150 T/Q/R/E
, and
N148S
in NTD may be responsible for antibody escape.
3
Omicron: A Heavily Mutated SARS-CoV-2 Variant Exhibits Stronger Binding to ACE2 and Potently Escapes Approved COVID-19 Therapeutic Antibodies.
PMID:
35140714
2021
Frontiers in immunology
Discussion:
N440K
and
K444Q
can escape against REGN10987, while
K417N
,
N460T
, and
A475V
can successfully escape against LY-CoV016 antibody (AbCellera), currently approved by the FDA for
COVID-19
therapy.
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Co-occurred Entities
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2021
Discussion
Introduction
35258772
35222380
35140714
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SARS_CoV_2 mutation literature information.
PMID: 
2022
Frontiers in immunology
Browser Board
Co-occurred Entities
Filtrator