SARS-CoV2 spike protein gene variants with N501T and G142D mutation-dominated infections in mink in the United States.
PMID: 34109885
2021
Journal of veterinary diagnostic investigation
Introduction: In addition to the above 3 mutations and 1 deletion in S protein, G614D, the mutation that dominated the SARS-CoV2 sequences, existed in all U.S.
Genomic Epidemiology of SARS-CoV-2 Infection During the Initial Pandemic Wave and Association With Disease Severity.
Figure: GISAID clades were further clustered into 2 clade groups depending on the presence of the G614D spike glycoprotein variant (black dashed line).
Immunity, virus evolution, and effectiveness of SARS-CoV-2 vaccines.
PMID: 33729394
2021
Brazilian journal of medical and biological research
Abstract: During the global pandemic, COVID-19 patients were identified with non-synonymous substitution of G614D in the spike protein, indicating virus co-evolution in host cells.
The immunodominant and neutralization linear epitopes for SARS-CoV-2.
Abstract: We find that the immunodominant epitopes of individuals with domestic (China) SARS-CoV-2 are different from those of individuals with imported (Europe) SARS-CoV-2, which may be caused by mutations on the S (G614D) and N proteins.
A main event and multiple introductions of SARS-CoV-2 initiated the COVID-19 epidemic in Greece.
Abstract: A dominant variant, encompassing the G614D amino acid substitution, spread through a major virus dispersal event, and sporadic introductions of rare variants characterized the local initiation of the epidemic.
Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus.
Figure: The frequency of the GR clade appears to be increased in the UK and Europe as a subset of the regional G clade expansion, given that both carry G614D.
Large scale genomic analysis of 3067 SARS-CoV-2 genomes reveals a clonal geo-distribution and a rich genetic variations of hotspots mutations.
Abstract: The phylogentic analysis identified two major Clades C1 and C2 harboring mutations L3606F and G614D, respectively and both emerging for the first time in China.
The D614G mutation in the SARS-CoV2 Spike protein increases infectivity in an ACE2 receptor dependent manner.
Introduction: By the time the epidemic reached Europe, a variant strain had appeared that carried a missense mutation in the Spike glycoprotein that substituted the aspartate at position 614 for a glycine in isolates identified in Germany, Italy and Mexico.
SARS_CoV_2 mutation literature information.
PMID: 
2021
Journal of veterinary diagnostic investigation
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