Abstract: Furthermore, deep-mutational scanning and in vitro escape selection experiments demonstrate that S2X259 possesses an escape profile that is limited to a single substitution, G504D.
The Progression of SARS Coronavirus 2 (SARS-CoV2): Mutation in the Receptor Binding Domain of Spike Gene.
5Result: The chromatographic DNA sequencing result of the four patients showed glycine 504 codon ""GGT"" (reference sequence) was substituted by aspartic acid 504 codon ""GAT"" (G504D)."
Figure: (A) The align of Korean COVID-19 and wild ype SARS-CoV2 spike gene amino acid sequence revealed three new mutations (G504D/V524D/P579L) highlighted by green with red letter.
Figure: The representative chromatography of D614G (A), G504D (B), V524D (C), and P579L (D) mutation was shown from the DNA sequencing results of four Korean COVID-19 patients.
SARS_CoV_2 mutation literature information.
PMID: 
2022
Nature communications
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