literature

SARS_CoV_2 mutation literature information.

The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity.

PMID: 32730807 2020 Cell

Result: These variants include single amino acid change such as Y145del, Q414E, N439K, G446V, K458N, I472V, A475V, T478I, V483I, F490L, and A831V, as well as the double amino acid changes including D614G+Q321L, D614G+I472V, D614G+A831V, D614G+A879S and

Table: G446V

A SARS-CoV-2 vaccine candidate would likely match all currently circulating variants.

PMID: 32868447 2020 Proc Natl Acad Sci U S A

Result: The others were nonsynonymous: G476S (n = 10 sequences, 0.05%), Y453F (n = 5, 0.02%), G446V (n = 3, 0.02%), and A475V (n = 2, 0.01%).

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