literature

SARS_CoV_2 mutation literature information.

Role of the Microbiome in the Pathogenesis of COVID-19.

PMID: 35433495 2022 Frontiers in cellular and infection microbiology

Table: G251V

Identification of genotypic variants and its proteomic mutations of Brazilian SARS-CoV-2 isolates.

PMID: 34740719 2022 Virus research

Table: G251V

D155Y substitution of SARS-CoV-2 ORF3a weakens binding with Caveolin-1.

PMID: 35126886 2022 Computational and structural biotechnology journal

Introduction: G251V and Q57H exhibit severe virulence property.Viral infection consists of several steps starting from viral entry, intracellular trafficking, replication, assembly and then release of the viral particles.

Introduction: The mutation patterns of ORF3a gene have been characterized as largely non-synonymous and increasingly deleterious (Q57H, H93Y, R126T, L127I, W128L, L129F, W131C, D155Y, D173Y, G196V, and G251V).

Worldwide SARS-CoV-2 haplotype distribution in early pandemic.

PMID: 35171928 2022 PloS one

Table: p.Gly251Val

Rapid SARS-CoV-2 Intra-Host and Within-Household Emergence of Novel Haplotypes.

PMID: 35215992 2022 Viruses

Result: At the gene level, G26144T mutation leads to an NS3:G251V amino acid change, which was reported to increase disease severity by 4.4 times.

Genomic Diversity of SARS-CoV-2 in Algeria and North African Countries: What We Know So Far and What We Expect?

PMID: 35208920 2022 Microorganisms

Abstract: Lower prevalence was noted for GRY (variant S-N501Y) (5.1%), S (variant ORF8-L84S) (3.1%) and GV (variant of the ORF3a coding protein NS3-G251V) (2.0%).

Phylogeography and genomic epidemiology of SARS-CoV-2 in Italy and Europe with newly characterized Italian genomes between February-June 2020.

PMID: 35388091 2022 Scientific reports

Result: Overall, the B sequences showed a distinct mutations pattern from those of other lineages, including mutations L3606F, G251V in orf1a and orf3a, respectively.

Table: G251V

Development of a genotyping platform for SARS-CoV-2 variants using high-resolution melting analysis.

PMID: 34154921 2021 Journal of infection and chemotherapy

Table: G251V

Quasispecies of SARS-CoV-2 revealed by single nucleotide polymorphisms (SNPs) analysis.

PMID: 34030593 2021 Virulence

Abstract: The positive selection analysis of the SARS-CoV-2 genome uncovered the positive selected amino acid G251V on ORF3a.

SARS-CoV-2 mutations: the biological trackway towards viral fitness.

PMID: 33928885 2021 Epidemiology and infection

Introduction: Among 51 non-synonymous mutations in ORF3a, Q57H (17.4%) and G251V (9.7%) were predominant ones of which Q57H mutation was found to cause disease severity in hospitalised.

Introduction: The clade G, S and V comprise variants of S:D614G (23403A>G), ORF8:L84S (8782C>T) and ORF3a:G251V (26144G>T), respectively (Table 2).

Table: G251V

Browser Board

Co-occurred Entities

Filtrator