literature

SARS_CoV_2 mutation literature information.

Spike protein cleavage-activation mediated by the SARS-CoV-2 P681R mutation: a case-study from its first appearance in variant of interest (VOI) A.23.1 identified in Uganda.

PMID: 34230931 2022 bioRxiv

Abstract: The A.23 viral lineage, characterized by three spike mutations F157L, V367F and Q613H, was first identified in COVID-19 cases from a Ugandan prison in July 2020, and then was identified in the general population with additional spike mutations (R102I, L141F, E484K and P681R) to comprise lineage A.23.1 by September 2020, with this virus being designated a variant of interest (VOI) in Africa and with subsequent spread to 26 other countries.

Introduction: Within lineage A, the A.23 viral lineage, was first identified in a Ugandan prison in July 2020, and was characterized by three spike mutations

Efficacy of mRNA, adenoviral vector, and perfusion protein COVID-19 vaccines.

PMID: 34906769 2022 Biomedicine & pharmacotherapy

Table: F157L

Viral transmission and evolution dynamics of SARS-CoV-2 in shipboard quarantine.

PMID: 34248221 2021 Bulletin of the World Health Organization

Result: For the spike protein, two mutations, F157L and G181V, were identified.

Table: F157L

Detection and characterization of the SARS-CoV-2 lineage B.1.526 in New York.

PMID: 34373458 2021 Nature communications

Table: F157L

Dynamics prediction of emerging notable spike protein mutations in SARS-CoV-2 implies a need for updated vaccines.

PMID: 34508827 2021 Biochimie

Introduction: PANGO reports, which are available online, currently include five linages; B.1.1.7 or known as UK linage (N501Y, P681H and other mutations), B.1.351 or known as South Africa linage (501Y.v2), P.1 or known as Brazil linage (E484K, N501Y and K417T), A.23.1 linage (F157L, V367F, Q613H and P681R) and B.1.525 linage (E484K, Q677H, F888L).

Serum Neutralizing Activity of mRNA-1273 against SARS-CoV-2 Variants.

PMID: 34549975 2021 Journal of virology

Table: F157L

Mutations in SARS-CoV-2 Leading to Antigenic Variations in Spike Protein: A Challenge in Vaccine Development.

PMID: 32884216 2020 Journal of laboratory physicians

Result: Furthermore, the evaluation of the antigenicity of spike protein predicted 14 highest scoring antigenic epitopes (antigenic scores >= 1.0) due to variations in each (at positions L54F, L54W, F55I, S71F, D111N, F157L, L293M, L293V, D294E, D294I,

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