Abstract: Structural analysis revealed that the S:D178H mutation is in the NTD of the S protein and close to two other signature mutations of B.1.1.7, HV69-70del and Y144del.
Figure: (A) Percentages of B.1.1.7 (blue) or B.1.1.7-M:V70L (orange) isolates that carried the S:D178H mutation from January to April 2021 in US and globally, respectively.
Figure: (B) Percentages of B.1.1.7 isolates that carried the S:D178H mutation from September 2020 to April 2021 in California.
Figure: (C) Percentages of B.1.1.7 is
Figure: Transmission of the 1026 B.1.1.7-MV70L-S:D178H isolates across the US.
Temporal-Geographical Dispersion of SARS-CoV-2 Spike Glycoprotein Variant Lineages and Their Functional Prediction Using in Silico Approach.