literature

SARS_CoV_2 mutation literature information.

Genomic Variations in SARS-CoV-2 Genomes From Gujarat: Underlying Role of Variants in Disease Epidemiology.

PMID: 33815459 2021 Frontiers in genetics

Table: C8782T

SARS-CoV-2 mutations: the biological trackway towards viral fitness.

PMID: 33928885 2021 Epidemiology and infection

Introduction: Cluster I includes 3037C>T; NSP3:F106F (non-structural protein3:F106F) and 14408C>T; RdRp:P323L, cluster II includes 3037C>T, 14408C>T and 23403A>G; S:D614G, cluster III includes 14408C>T, cluster IV includes 3037C>T, 14408C>T, 23403A>G, 28881G>A; N:R203K, 28882G>A

Characterization of SARS-CoV-2 different variants and related morbidity and mortality: a systematic review.

PMID: 34103090 2021 European journal of medical research

Table: C8782T

Discussion: In other words, the S variant (Type A) with two mutations at 8782C>T and 28144 T>C was mainly identified in East Asia.

Development of a genotyping platform for SARS-CoV-2 variants using high-resolution melting analysis.

PMID: 34154921 2021 Journal of infection and chemotherapy

Table: C8782T

AutoVEM2: A flexible automated tool to analyze candidate key mutations and epidemic trends for virus.

PMID: 34512928 2021 Computational and structural biotechnology journal

Method: In our study in the early stage of the pandemic (2019.12 - 2020.05.05), we found 9 specific mutation sites (C241T, C3037T, C8782T, C14408T, C17747T, A17858G, C18060T, A23403G, and T28144C) of SARS-CoV-2.

Bioinformatic analysis of the whole genome sequences of SARS-CoV-2 from Indonesia.

PMID: 34540148 2021 Iranian journal of microbiology

Table: C8782T

Identification and characterization of SARS-CoV-2 clusters in the EU/EEA in the first pandemic wave: additional elements to trace the route of the virus.

PMID: 34637920 2021 Infection, genetics and evolution

Result: SS1 carried the signature mutations C8782T and T28144C, the last resulting in the amino acid (AA) change L > S in the ORF8 protein.

Table: C8782T

Host Response to SARS-CoV2 and Emerging Variants in Pre-Existing Liver and Gastrointestinal Diseases.

PMID: 34760721 2021 Frontiers in cellular and infection microbiology

Introduction: Lineage-A variants mostly harbor two unique mutations (8782 C>T and 28144 T>C), which are absent in Lineage-B variants.

Introduction: The early splits of phylogenetic clades were S (marker C8782T, T28144C and NS8-L84S) and L (C241, C3037, A23403, C8782, G11083, G26144, T28144).

Emergence of B.1.524(G) SARS-CoV-2 in Malaysia during the third COVID-19 epidemic wave.

PMID: 34764315 2021 Scientific reports

Result: Besides the GISAID clade S-specific genetic markers, C8782T and T28144C, there were no other shared mutations between these two samples.

Table: C8782T

A Conservative Replacement in the Transmembrane Domain of SARS-CoV-2 ORF7a as a Putative Risk Factor in COVID-19.

PMID: 34943191 2021 Biology

Abstract: 9659 in ORF-10, 8782C > T in ORF-1ab, or 28144T > C in ORF-8, have been proposed for altering SARS-CoV-2 virulence and pathogenicity.

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