Discussion: C28854T substitution in the nucleocapsid protein coding region, which leads to an amino acid change (S194L), was another missense mutation that also was seen in 6/95 samples in a previous study where 95 sequences from different countries were evaluated (Wang et al., 2020).
The Novel Coronavirus Enigma: Phylogeny and Analyses of Coevolving Mutations Among the SARS-CoV-2 Viruses Circulating in India.
PMID: 33496683
2020
JMIR bioinformatics and biotechnology
Result: Intriguingly, 28854C>T (S194L) in the N gene was found to coevolve with the 22444C>T (D294D) mutation in the S gene of 11 samples in the major group (Table 1).
Result: Out of the 67 isolates of the major group, 28 revealed 4 novel mutations: 28854C>T (S194L; n=13), 28881-28883GGG>AAC (R203K and G204R; n=13), and coevolving mutation 29451C>T (T393I) and 28395G>A (R41R; n=2) in the N gene (Table 1).
SARS_CoV_2 mutation literature information.
PMID: 
2020
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