Introduction: We have previously sequenced the SARS-CoV-2 viral genome isolated from a group of 62 Romanian patients during first
COVID-19 outbreak and identified several mutations, one of which occurred at position 27,707 (
C27707T) which leads to a substitution of alanine to valine (
A105V) in the transmembrane domain of SARS-CoV-2
ORF7a.