literature

SARS_CoV_2 mutation literature information.

Emergence of B.1.524(G) SARS-CoV-2 in Malaysia during the third COVID-19 epidemic wave.

PMID: 34764315 2021 Scientific reports

Result: The T19524 and T19524T-A6210 strains were also detected in neighboring countries including Singapore, Thailand, and Australia (https://bigd.big.ac.cn/ncov/) but not the T19524-A6210-A2508 strains, suggesting the C2508A could be a mutation that accumulated in the SARS-CoV-2 gene pool during the second COVID-19 epidemic wave in Malaysia.

Result: Within B.6(O), another group with the additional mutation, C19524T, was observed; subsequently, an additional C6210A and then C2508A was detected in a subset of this group (B.6.6(O)).

Table: C2508A

SARS-CoV-2 lineage B.6 was the major contributor to early pandemic transmission in Malaysia.

PMID: 33253226 2020 PLoS neglected tropical diseases

Result: Some mutations were unique to Malaysian B.6 genomes, such as C2508A, A3223G, C9438T, C9803T, C13329T, C20823T, C26607T, A29086T and C29218T; others, including C6310A, T7621C and C19524T, were also observed in B.6 sequences from other countries including Singapore, Australia and India (Fig 3).

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