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 SARS_CoV_2 mutation literature information.


  Examining the interactions scorpion venom peptides (HP1090, Meucin-13, and Meucin-18) with the receptor binding domain of the coronavirus spike protein to design a mutated therapeutic peptide.
 PMID: 34119951       2021       Journal of molecular graphics & modelling
Abstract: The results revealed that the A9T mutation had more effective interaction with the RBD domain than the meucin-18 and was able to inhibit spike protein's interaction with ACE2 receptor.
Method: Then, the first five suggested mutations of BeAtMuSiC server containing A9T, H4Y, A9S, H4F, K7H plus the combination of mutation one and four (A9T + H4F) (in total six mutations) were generated via SPDV Swiss-PDB viewer (https://spdbv.vital-it.ch/) in the final structure of meucin-18 peptide (that was gained from 100 ns MD simulation) distinctly.
Result: According to docking results, mutation 2 (H4Y) of the meucin-18



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