The low contagiousness and new A958D mutation of SARS-CoV-2 in children: An observational cohort study.
PMID: 34454120
2021
International journal of infectious diseases
Abstract: The new A958D mutation is a potential reason for its long residence in the intestine.
Abstract: We obtained SARS-CoV-2 sequences from the same infant's throat and fecal samples at a two-month interval and found that the new spike protein A958D mutation detected in the stool improved thermostability theoretically.
Result: Among these mutations, the new A958D mutation of the spike protein (24435C>A mutation in the virus genome) is of special interest because it is the only one for which the 3D structure of the protein has been solved.
Result: The new A958D mutation improves theoretically viral thermostability.
Result: The structure suggests that the A958D mutation will lead to s
SARS_CoV_2 mutation literature information.
PMID: 
2021
International journal of infectious diseases
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