Result: Additionally, whereas a convergent A701V mutation is also found in the B.1.526 and S/E484K carrying lineage that was first identified in New York, P681H is found in the S/E484K and S/N501Y carrying P.3 lineage first identified in the Philippines, and both S/H655Y and S/P681H are found in the highly mutated S/E484K carrying A.VOI.V2 lineage first identified in Tanzanian travellers.
Result: Any of H655Y, P681H, A701V or T716I might directly impact the efficiency of viral entry into host cells.
Result: Whereas sites S/655,
Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies.
Result: We created a chimeric, fully-infectious SARS-CoV-2 with a South African spike gene (Wash SA-B.1.351; D80A, 242-244 deletion, R246I, K417N, E484K, N501Y, D614G, and A701V) and a panel of isogenic spike mutants (D614G, K417N/D614G, E484K/D614G, N501Y/D614G, P681H/D614G, del69-70/N501Y/D614G,
Emergence and Expansion of the SARS-CoV-2 Variant B.1.526 Identified in New York.
Introduction: Nearly all of the newly identified B.1.526 variants have a set of common mutations in the spike protein: L5F, T95I, D253G, E484K, D614G, and A701V.
Introduction: The A701V mutation near the furin cleavage site is also shared with variant B.1.351.
Crucial Mutations of Spike Protein on SARS-CoV-2 Evolved to Variant Strains Escaping Neutralization of Convalescent Plasmas and RBD-Specific Monoclonal Antibodies.
Introduction: In addition, several recent studies have focused on the neutralizing activity of vaccine-elicited humoral immunity against new circulating mutant lineages, including B.1.1.7 (United Kingdom, bearing mutations 69-70 del, 144 del, N501Y, A570D, D614G, P681H, T716I, S982A, and D1118H in the spike protein), B.1.429 (United States, bearing mutations S13I, W152C, L452R, and D614G in the spike protein), B.1.351(South Africa, bearing mutations D80A, D215G, PMID: 34700382
2021
mBio
Result: A total of 139 unique S protein variants of beta (B.1.351) were clustered, with the majority carrying 7 consensus amino acid variations (D80A, D215G, K417N, E484K, N501Y, D614G, and A701V) and 1 deletion (amino acid 242).
Table: A701V/S
Prior infection with SARS-CoV-2 boosts and broadens Ad26.COV2.S immunogenicity in a variant-dependent manner.
Method: SARS-CoV-2 pseudotyped lentiviruses were prepared by co-transfecting the HEK293T cell line with either the SARS-CoV-2 ancestral variant spike (D614G), the Beta spike (L18F, D80A, D215G, K417N, E484K, N501Y, D614G, A701V, 242-244 del) or the Delta spike (T19R, R158G L452R, T478K, D614G, P681R, Table: A701V
Evaluation of the clinical and analytical performance of the Seegene allplex SARS-CoV-2 variants I assay for the detection of variants of concern (VOC) and variants of interests (VOI).
Result: The Beta S is comprised of the L18F, D80A, D215G, and 242-244 mutations in the NTD, K417N and E484K mutations in the receptor-binding domain (RBD), and A701V in the S1/S2 cleavage site.
Emergence and Spread of a B.1.1.28-Derived P.6 Lineage with Q675H and Q677H Spike Mutations in Uruguay.
Discussion: Moreover, mutations close to or at the polybasic cleavage site at the S1/S2 boundary have been reported in several VOCs and VOIs, including: Alpha (S:P681H), Beta (A701V), Delta (P681R), Eta (Q677H), Iota (A701V), Kappa (P681R), and Theta (P.3, P681H).
SARS_CoV_2 mutation literature information.
PMID: 
2021
Reviews in medical virology
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