Result: Aside from this synonymous mutation, all C2 sequences carried other five m
Discussion: For example, the parent node sequences of C1 containing C2416T/C3037T/C14408T/A23403G/G25563T was reported to be associated with an international business conference in Boston, resulting in extensive international spread and low-level community transmission in Europe.
Discussion: Genomes of another sister cluster C2, harboring the C26735T variant in addition to common signatures of C3037T/C14408T/A23403G/C18877T/G25563T, have been found mainly in Asia (93 genomes as of October 9, 2020).
Detailed phylogenetic analysis tracks transmission of distinct SARS-COV-2 variants from China and Europe to West Africa.
Introduction: In Europe the first German sample from January 28th carried the A-to-G mutation at nucleotide position 23403 (D614G) mutation and the C-to-T mutation at position 3037, but not the mutation at position 14408.
Introduction: One sample from Jan
Result: The split of the tree by the A23403G (D614G) substitution into two major branches corresponds to the highest diversity found at that location.
Result: The tree can be divided into two major branches resulting from the A23403G (D614G) substitution.
Figure: (b) Highest diversity is at the A23403G (D614G) substitution splitting the tree in the bottom (Chinese) and top (European) branch.
Analysis of 329,942 SARS-CoV-2 records retrieved from GISAID database.
PMID: 34735950
2021
Computers in biology and medicine
Abstract: Clustering results suggested that a proportion of people (2.46%) was infected with a distinct subtype of the B.1.1.7 variant, which contained four to six additional mutations (G28881A, G28882A, G28883S, A23403G, A28095T, G25437T).
Result: Four mutations were present in the cluster with 100% frequency - G28881A, G28882A, G28883C, and A23403G.
Result: Mutations found in samples uploaded mainly by Denmark and Australia formed two clusters, each containing 8 mutations (sizes regarding all studied genomes - 1.48% and 2.51%, respectively): C26735T (100%), PMID: 34748557
2021
PloS one
Result: Excluding the substitution at position 241 in the 5' UTR, the top three most frequent mutations were the C3037T (59.9%), C14408T (59.9%) and A23403G (D614G) (57.4%).
Result: From March to December, substitutions appeared consistently at the genomic positions C241T, C3037T, C14408T and A23403G.
Result: The second LD set comprised C3037T, C14408T and A23403G mutations in viruses isolated from March to December and involving a single synonymous and non-synonymous mutation in ORF1ab, together with a si
Host Response to SARS-CoV2 and Emerging Variants in Pre-Existing Liver and Gastrointestinal Diseases.
PMID: 34760721
2021
Frontiers in cellular and infection microbiology
Introduction: Further, L clade evolved to V (G11083T, G26144T, NSP6-L37F + NS3-G251V) and G (C241T, C3037T, A23403G, and S-D614G); and later G clade evolved into GH (C241T, C3037T, A23403G, G25563T includes S-D614G + NS3-Q57H), GR (C241T, C3037T,
Emergence of B.1.524(G) SARS-CoV-2 in Malaysia during the third COVID-19 epidemic wave.
Result: All strains clustered under this group, including those sequenced in the current study, possessed the three GISAID clade G genetic variants, C241T, C3037T, and A23403G with an additional mutation C14408T.
Result: Based on the GISAID clade assignment, the samples detected during early April 2020 (4Apr20-3-Hu/2020 and 5Apr20-64-Hu/2020), and all samples detected in October 2020 (third epidemic wave) denoted clade G (Table 1), possessed genetic variations at C241T, C3037T, and A23403G.
Result: The A23403G was encoded for substitution of aspartic acid with glycine in the S-614 (S-D614G)
An outbreak of SARS-CoV-2 with high mortality in mink (Neovison vison) on multiple Utah farms.
Result: Synonymous SNPs from this Farm A isolate included C1059T, C3037T, C6336T, G12795A, C14408T, C20930T, A23064C, A23403G, G25563T, C25936T, C28887T, were also identical to those of MW474212 from a human in Washington State.
Genome-wide identification and prediction of SARS-CoV-2 mutations show an abundance of variants: Integrated study of bioinformatics and deep neural learning.
PMID: 34812411
2021
Informatics in medicine unlocked
Result: The A23403G mutation causes a change from Aspartate (D) to Glycine (G) in protein position 614 (spike protein) which is responsible for the initial entry of the virus through the ACE2 receptor and is associated with the severity of COVID 19.
Figure: The A23403G, C3037T, C14408T, and C241T are the most widespread mutations globally.
A next generation sequencing (NGS) analysis to reveal genomic and proteomic mutation landscapes of SARS-CoV-2 in South Asia.
PMID: 34841355
2021
Current research in microbial sciences
Result: A total of 12 mutations were found in Germany in which four mutations 241C > T, 3037C > T, 14408C > T and 23403A > G were found common and existed at a frequency of 87.38%, 89.32%, 77.62% and 88.35%, respectively.
Result: After analyzing the samples of Brazil, a total of 12 mutations were found in which four of them (241C > T, 3037C > T, 14408C > T and 23403A > G) were identified at a frequency of 100%.
Result: Among all of these alterations originated from North America, South America and European regions, five SNPs (241C > T, 3037C > T, 14408C > T,
ViMRT
SARS_CoV_2 mutation literature information.
PMID: 
2021
Genomics, proteomics & bioinformatics
