literature

SARS_CoV_2 mutation literature information.

SARS-CoV-2 outbreak in Iran: The dynamics of the epidemic and evidence on two independent introductions.

PMID: 33835709 2022 Transboundary and emerging diseases

Result: Other less frequent variants were observed in ~19% of samples constituting the known co-occurrence of variants; [C241T-C3037T-C14408T-A23403G] and [C241T-C3037T-C14408T-A23403G-G25563T], occurring in clade G (B.1), which is prevalent in Europe, Oceania, South America and Africa and clade GH (B.1.*), prevalent in North America (Mercatelli and Giorgi, 2020).

Result: The [B.1.*/20A] samples did not show [G1397A-T28688C-G29742T] substitutions but instead harboured [ Table: A23403G

Genomic Surveillance of SARS-CoV-2 Lineages Indicates Early Circulation of P.1 (Gamma) Variant of Concern in Southern Brazil.

PMID: 35171035 2022 Microbiology spectrum

Table: A23403G

SARS-CoV-2 genomes from Saudi Arabia implicate nucleocapsid mutations in host response and increased viral load.

PMID: 35105893 2022 Nature communications

Result: Similarly, the model showed a positive significant association between the SNPs A23403G (Spike protein D614G) and C26735T SNPs and log10(viral copy number), the former being consistent with earlier reports.

Result: The A23403G mutation results in the Spike protein D614G SNP that is associated with higher viral load.

Result: These include the Spike protein D614G (A23403G) and three consecutive SNPs (G28881A, G28882A, and G28883C) causing the R203K and

Evidence of a SARS-CoV-2 double Spike mutation D614G/S939F potentially affecting immune response of infected subjects.

PMID: 35096288 2022 Computational and structural biotechnology journal

Result: In particular, S939F variant, due to nucleotide change C to T in position 24378 of Spike gene, resulted to be about three hundred times less frequent than D614G variant, due to nucleotide change A to G in position 23403 (3853 versus 1218522 counts), determining an evidence level of IV for S939F versus I for D614G.

Emergence of two distinct variants of SARS-CoV-2 and an explosive second wave of COVID-19: the experience of a tertiary care hospital in Pune, India.

PMID: 35000004 2022 Archives of virology

5Result: The four mutations, C241T, C3037T, C14408T, and A23403G, were observed in all 20 genome sequences from the clade ""G"" isolates (named after the D614G mutation)."

Cross-sectional genomic perspective of epidemic waves of SARS-CoV-2: A pan India study.

PMID: 34822953 2022 Virus research

Table: A23403G

Prevalence of a Single-Nucleotide Variant of SARS-CoV-2 in Korea and Its Impact on the Diagnostic Sensitivity of the Xpert Xpress SARS-CoV-2 Assay.

PMID: 34374354 2022 Annals of laboratory medicine

Introduction: The SNVs that define B.1.497 include C241T, C1059T, C11916T, C14408T, C16560T, A20675T, A23403G, G25563T, and G29179T.

Genotype-phenotype correlation identified a novel SARS-CoV-2 variant possibly linked to severe disease.

PMID: 33506644 2022 Transboundary and emerging diseases

Result: Some mutations were more frequent than others; for example, the 241C>T, 3037C>T, 14408C>T, and the 23403A>G (also known as the D614G mutation in the S protein), were each seen in 58 of the genomes (Table S3).

The twin-beginnings of COVID-19 in Asia and Europe-one prevails quickly.

PMID: 35497643 2022 National science review

Abstract: The first wave is a group of four mutations (C241T, C3037T, C14408T and A23403G [this being the amino acid change D614G]; all designated 0 to 1 below).

Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation.

PMID: 34823256 2022 Nature

Figure: b, Chromatograms of nucleotide positions 23,399-23,407 (left) and 23,600-23,608 (right) of parental SARS-CoV-2 (strain WK-521, PANGO lineage A; GISAID ID: EPI_ISL_408667) and the D614G (A23403G in nucleotide) and P681R (C23604G in nucleotide) mutations.

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