literature

SARS_CoV_2 mutation literature information.

Comprehensive annotations of the mutational spectra of SARS-CoV-2 spike protein: a fast and accurate pipeline.

PMID: 32954666 2021 Transboundary and emerging diseases

Table: A222V

Dynamics of SARS-CoV-2 mutations reveals regional-specificity and similar trends of N501 and high-frequency mutation N501Y in different levels of control measures.

PMID: 34493762 2021 Scientific reports

Result: 2b (I33T), c (A222V), and d (P67S)).

An innovative approach for the non-invasive surveillance of communities and early detection of SARS-CoV-2 via solid waste analysis.

PMID: 34467913 2021 The Science of the total environment

Abstract: Amino acid substitutions already reported in SARS-CoV-2 sequences circulating in Italy (A222V and P521S) were detected in two positive samples.

Result: Compared to the W

Table: A222V

SARS-CoV-2 reinfection in a healthcare professional in inner Sao Paulo during the first wave of COVID-19 in Brazil.

PMID: 34425504 2021 Diagnostic microbiology and infectious disease

Table: A222V

Evolutionary analysis of the Delta and Delta Plus variants of the SARS-CoV-2 viruses.

PMID: 34399188 2021 Journal of autoimmunity

Abstract: Furthermore, five key mutations (T95I, A222V, G142D, R158G, and K417N) were significantly more prevalent in the Delta Plus than in the Delta variant.

Abstract: Signature mutations in Spike (G142D, A222V, and T95I) existed at a more significant percentage in the Delta Plus variant than the Delta variant.

Introduction: According to the United States (US) Center for Disease Control (CDC), signature Spike mutations in the aggregated Delta and Delta Plus variant include T19R, (V70F*), T95I, G142D

Infection-enhancing anti-SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and Delta variants. A potential risk for mass vaccination?

PMID: 34384810 2021 The Journal of infection

Introduction: - T19R/E156G/del157/del158/A222V (B.1.617.2).

Molecular Evolution and Epidemiological Characteristics of SARS COV-2 in (Northwestern) Poland.

PMID: 34372500 2021 Viruses

Result: Of note, when excluding the B.1.1.7 variant from temporal trends analysis, only four mutations (delH69V70, P681H, S98F, A222V) had a significantly different frequency from November 2020 until February 2021 (see Figure S5 and Table S4).

Result: The first one was DeltaH69V70 and N439 in lineage B.1.258 (20A), then D138Y with S477N observed for B.1.1.317 (20B), and finally A222V and L18F in the B.1.177 (20E EU1) strains.

SARS-CoV-2 Spike Mutations, L452R, T478K, E484Q and P681R, in the Second Wave of COVID-19 in Maharashtra, India.

PMID: 34361977 2021 Microorganisms

Result: Similarly, mutations K77T and A222V were found in a proportion of B.1.617.2.

Correlates of SARS-CoV-2 Variants on Deaths, Case Incidence and Case Fatality Ratio among the Continents for the Period of 1 December 2020 to 15 March 2021.

PMID: 34356077 2021 Genes

Result: The Spike_A222V mutation was reported at 26.59% in SARS-CoV-2 genome sequences isolated from Europe.

Modelling conformational state dynamics and its role on infection for SARS-CoV-2 Spike protein variants.

PMID: 34351895 2021 PLoS computational biology

Conclusion: The A222V mutation, reportedly responsible for many infections, emerged in Spain during the Summer of 2020 and since then has spread to neighbor countries; In Denmark, new strains related to SARS-CoV-2 transmission in mink farms were confirmed in early October by the WHO and shown to be caused by specific mutations not previously observed with the novelty of back-and-forth transmission between minks and humans.

Result: The recently observed A222V mutation on the other hand, does not show in our analysis any propensity of altering the occupancy of states with a negative VDS of -1.64x10-2 J.K-1.

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