PA from a Recent H9N2 (G1-Like) Avian Influenza a Virus (AIV) Strain Carrying Lysine 367 Confers Altered Replication Efficiency and Pathogenicity to Contemporaneous H5N1 in Mammalian Systems.
Discussion: Except for NP segment from H5N1/Q4596D, all internal protein-encoding segments were compatible with the complementary seven segments from H9N2/S4456B and viruses could be rescued.
Discussion: In complement to this study, we previously tested the genetic compatibility of viral segments derived from HPAI A/duck/Egypt/Q4596D/2012 (H5N1) (H5N1/Q4596D) in the genetic backbone of LPAI A/chicken/Egypt/S4456B/2011 (H9N2) (H9N2/S4456B) using Rg approach of influenza viruses.
IV mutation literature information.
PMID: 
2020
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