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 IV mutation literature information.


  Identification of Important N-Linked Glycosylation Sites in the Hemagglutinin Protein and Their Functional Impact on DC-SIGN Mediated Avian Influenza H5N1 Infection.
 PMID: 33451024       2021       International journal of molecular sciences
Result: Combined, these results suggest that mutation on N27 or N39 N-glycosylation site or both sites of HA ameliorate DC-SIGN mediated H5N1 infection in cis.
Result: However, H5N1-PVs with N181Q mutation did not influence DC-SIGN mediated H5N1 trans infection (p > 0.05), indicating most attenuated effect was resulted from N27 and N39 N-glycosylation mutation (Figure 6C).



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