Result: We found that the same amount of vRNA bound more WSN-H1PB1494-757 protein than WSN-H1PB1494-757/K612R protein (Fig 8K).
Figure: (B) HEK293T cells were transfected with plasmids encoding Flag-tagged WSN-H1PB1 or its potential SUMOylation site mutant WSN-H1PB1/K379R, WSN-H1PB1/K612R, or WSN-H1PB1/K736R, together wi
Figure: (C) PB1/K612R mutation does not affect the PB1-PA interaction.
Figure: (G-I) Growth curves of WSN (H1N1) or WSN-PB1K612R (H1N1) (G), VN/1180 (H5N1) or VN/1180-PB1K612R (H5N1) (H), and AH/1 (H7N9) or AH/1-PB1K612R (H7N9) (I).
IV mutation literature information.
PMID: 
2021
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