literature

IV mutation literature information.

Identification of two residues within the NS1 of H7N9 influenza A virus that critically affect the protein stability and function.

PMID: 30285871 2018 Veterinary research

Method: The H7N9 NS1 mutants, NS1 (R55E), NS1 (H63Q), NS1 (E70K), NS1 (P87S), NS1 (S114P), NS1 (A143T), NS1 (I178V) and NS1 (S212P) were generated by site-directed mutagenesis with the QuickChange XL system (Stratagene, La Jolla, CA, USA).

Result: The substitutions were the following (avian_residue/Position/human_residue): R55E,

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