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 IV mutation literature information.


  Altering Intracellular Localization of the RNA Interference Factors by Influenza A Virus Non-structural Protein 1.
 PMID: 33281788       2020       Frontiers in microbiology
Result: We found that infection with the same dose of PR8-NS1 (D101H) caused significantly earlier mortality compared with IAV-PR8 infection (Figure 5A).
Figure: (B) Representative lung IHC slice images of BALB/c mice intranasally inoculated with Mock (left panel), PR8 WT virus (middle panel)
Figure: Mock infected (n = 5); PR8 WT infected (n = 10); PR8 D101H infected (n = 10).



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